Tyr62

Site Information
QRkDsEGysESPDLE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4755889

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	breast cancer ( 1 )
Relevant cell line - cell type - tissue:	293GP (epithelial) [NPM-ALK (human), transfection] ( 2 ) , Jurkat (T lymphocyte) ( 3 ) , SKBr3 (breast cell) ( 1 )

References
1	Imami K, et al. (2012) Temporal profiling of lapatinib-suppressed phosphorylation signals in EGFR/HER2 pathways. Mol Cell Proteomics 11, 1741-57 22964224 Curated Info
2	Wu F, et al. (2010) Studies of phosphoproteomic changes induced by nucleophosmin-anaplastic lymphoma kinase (ALK) highlight deregulation of tumor necrosis factor (TNF)/Fas/TNF-related apoptosis-induced ligand signaling pathway in ALK-positive anaplastic large cell lymphoma. Mol Cell Proteomics 9, 1616-32 20393185 Curated Info
3	Possemato A (2008) CST Curation Set: 5316; Year: 2008; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Curated Info