Thr224

Site Information
RVPAEDEtQsIDsED SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4742769

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 4 )
Disease tissue studied:	breast cancer ( 1 ) , lung cancer ( 4 ) , non-small cell lung cancer ( 4 )
Relevant cell line - cell type - tissue:	H2009 (pulmonary) ( 4 ) , H2887 (pulmonary) ( 4 ) , HCC2279 (pulmonary) ( 4 ) , HCC366 (pulmonary) ( 4 ) , HCC78 (pulmonary) ( 4 ) , HMLER ('stem, breast cancer') [CXCR4 (human), knockdown] ( 1 ) , HMLER ('stem, breast cancer') ( 1 ) , HOP62 (pulmonary) ( 4 ) , liver ( 2 ) , NCI-H1395 (pulmonary) ( 4 ) , NCI-H2030 (pulmonary) ( 4 ) , NCI-H2172 (pulmonary) ( 4 ) , NCI-H322 (pulmonary) ( 4 )

References
1	Yi T, et al. (2014) Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells. Proc Natl Acad Sci U S A 111, E2182-90 24782546 Curated Info
2	Bian Y, et al. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J Proteomics 96, 253-62 24275569 Curated Info
3	Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96 23911959 Curated Info
4	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
5	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info