Ser36

Site Information
EEQAFkRsRNtDEMV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4710516

In vivo Characterization
Methods used to characterize site in vivo:	2D analysis ( 1 ) , mass spectrometry ( 1 , 3 , 5 , 6 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	'3T3-L1, differentiated' (adipocyte) ( 3 , 5 ) , 'fat, brown' ( 6 ) , brain ( 6 ) , HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , kidney ( 6 ) , liver ( 6 ) , lung ( 6 ) , pancreas ( 6 ) , spleen ( 6 ) , testis ( 6 )

Upstream Regulation
Treatments:	insulin ( 5 ) , LY294002 ( 5 )

References
1	Kim HJ, et al. (2017) Heterogeneous nuclear ribonucleoprotein K inhibits heat shock-induced transcriptional activity of heat shock factor 1. J Biol Chem 292, 12801-12812 28592492 Curated Info
2	Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250 27841257 Curated Info
3	Parker BL, et al. (2015) Targeted phosphoproteomics of insulin signaling using data-independent acquisition mass spectrometry. Sci Signal 8, rs6 26060331 Curated Info
4	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
5	Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20 23684622 Curated Info
6	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info