Thr27
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Home > Phosphorylation Site Page: > Thr27  -  ID2 (mouse)

Site Information
LGISRsKtPVDDPMS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4706880

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
brain cancer ( 1 ) , glioblastoma ( 1 ) , glioma ( 1 )
Relevant cell line - cell type - tissue:
'stem, neural' ( 1 ) , U87MG (glial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
DYRK1A (human) ( 1 )

Downstream Regulation
Effects of modification on ID2:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell growth, inhibited ( 1 )
Inhibit interaction with:
VHL (mouse) ( 1 )

References 

1

Lee SB, et al. (2016) An ID2-dependent mechanism for VHL inactivation in cancer. Nature 529, 172-7
26735018   Curated Info

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