Ser14
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Home > Phosphorylation Site Page: > Ser14  -  ID2 (mouse)

Site Information
VRSVRKNsLSDHSLG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4706868

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 3 , 4 , 5 , 6 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
'brain, hippocampus' ( 1 ) , kidney ( 6 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 4 ) , spleen ( 6 ) , stromal ( 3 ) , T lymphocyte-spleen ( 5 )

Upstream Regulation
Treatments:
ischemia ( 3 )

Downstream Regulation
Effects of modification on biological processes:
cell growth, induced ( 1 ) , neural plasticity ( 1 ) , transcription, altered ( 1 )

References 

1

Luo W, et al. (2021) Recurrent rewiring of the adult hippocampal mossy fiber system by a single transcriptional regulator, Id2. Proc Natl Acad Sci U S A 118
34599103   Curated Info

2

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

3

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

4

Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22
21659604   Curated Info

5

Navarro MN, et al. (2011) Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes. Nat Immunol 12, 352-61
21399638   Curated Info

6

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

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