Ser357
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Home > Phosphorylation Site Page: > Ser357  -  CTNND2 (mouse)

Site Information
IGTyATLsPtKRLVH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4697626

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phospho-antibody ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
'neuron, cortical' ( 2 ) , 293 (epithelial) ( 2 ) , brain ( 1 , 2 ) , brain [CDK5 (mouse), homozygous knockout] ( 2 )

Upstream Regulation
Putative in vivo kinases:
CDK5 (human) ( 2 )
Kinases, in vitro:
CDK5 (mouse) ( 2 )

Downstream Regulation
Effects of modification on CTNND2:
intracellular localization ( 2 ) , molecular association, regulation ( 2 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 2 )
Inhibit interaction with:
GRIP1 (mouse) ( 2 ) , PSD-95 (mouse) ( 2 )

References 

1

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

2

Poore CP, et al. (2010) Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activity. J Neurosci 30, 8457-67
20573893   Curated Info