Thr344
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Home > Phosphorylation Site Page: > Thr344  -  Mnk1 (mouse)

Site Information
APERGLPtPQVLQRN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447623

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) [EIF4E (mouse)] ( 1 ) , MEF (fibroblast) [Mnk1 (mouse)] ( 1 )

Downstream Regulation
Effects of modification on Mnk1:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
cell growth, altered ( 1 ) , translation, altered ( 1 )

References 

1

Wendel HG, et al. (2007) Dissecting eIF4E action in tumorigenesis. Genes Dev 21, 3232-7
18055695   Curated Info

2

Waskiewicz AJ, Flynn A, Proud CG, Cooper JA (1997) Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2. EMBO J 16, 1909-20
9155017   Curated Info

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