[32P] bio-synthetic labeling ( 552 , 563 ) , flow cytometry ( 15 , 46 , 49 , 60 , 93 , 94 , 179 , 202 , 286 , 301 , 354 , 356 ) , immunoassay ( 7 , 23 , 38 , 39 , 54 , 57 , 58 , 61 , 66 , 67 , 75 , 89 , 90 , 101 , 102 , 104 , 113 , 115 , 122 , 129 , 131 , 147 , 156 , 164 , 170 , 244 , 265 , 278 , 279 ) , immunoprecipitation ( 94 , 193 , 198 , 202 , 203 , 221 , 240 , 241 , 252 , 267 , 277 , 282 , 321 , 328 , 367 , 371 , 383 , 398 , 582 , 583 ) , mass spectrometry ( 193 , 204 , 207 , 217 , 255 , 262 , 424 ) , mass spectrometry (in vitro) ( 252 , 320 ) , microscopy-colocalization with upstream kinase ( 397 ) , mutation of modification site ( 77 , 94 , 147 , 203 , 252 , 277 , 292 , 333 , 373 , 386 , 388 , 432 , 440 , 469 , 504 , 506 , 514 , 520 , 552 , 563 , 566 , 570 , 583 ) , peptide sequencing ( 345 , 507 ) , phospho-antibody ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 145 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 167 , 169 , 170 , 171 , 175 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 184 , 185 , 186 , 188 , 190 , 191 , 192 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 , 213 , 214 , 215 , 216 , 217 , 219 , 220 , 221 , 222 , 223 , 224 , 225 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 234 , 235 , 236 , 237 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 246 , 247 , 249 , 250 , 252 , 253 , 254 , 256 , 257 , 258 , 259 , 260 , 261 , 263 , 264 , 265 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , 278 , 279 , 281 , 282 , 283 , 284 , 285 , 287 , 288 , 289 , 290 , 291 , 292 , 294 , 295 , 296 , 299 , 300 , 302 , 303 , 304 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 314 , 315 , 316 , 317 , 318 , 319 , 320 , 321 , 323 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 334 , 335 , 336 , 337 , 338 , 339 , 340 , 341 , 342 , 343 , 344 , 346 , 347 , 348 , 349 , 350 , 351 , 352 , 353 , 354 , 355 , 356 , 357 , 358 , 359 , 360 , 361 , 362 , 363 , 364 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 , 373 , 374 , 376 , 377 , 378 , 379 , 380 , 381 , 382 , 383 , 384 , 385 , 386 , 388 , 389 , 390 , 391 , 393 , 394 , 395 , 396 , 397 , 398 , 399 , 401 , 402 , 403 , 404 , 405 , 406 , 407 , 408 , 409 , 410 , 411 , 412 , 413 , 414 , 415 , 416 , 418 , 419 , 420 , 421 , 422 , 423 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 434 , 435 , 436 , 437 , 438 , 440 , 441 , 442 , 443 , 444 , 446 , 447 , 448 , 449 , 450 , 451 , 452 , 453 , 454 , 455 , 456 , 457 , 458 , 459 , 460 , 461 , 462 , 463 , 464 , 465 , 466 , 468 , 469 , 470 , 471 , 472 , 473 , 474 , 475 , 477 , 478 , 479 , 480 , 482 , 483 , 484 , 485 , 486 , 487 , 488 , 489 , 490 , 491 , 492 , 493 , 494 , 495 , 496 , 497 , 499 , 500 , 501 , 502 , 503 , 504 , 505 , 506 , 508 , 509 , 510 , 511 , 512 , 513 , 514 , 515 , 516 , 518 , 519 , 520 , 521 , 522 , 523 , 524 , 525 , 526 , 527 , 528 , 529 , 530 , 531 , 532 , 533 , 534 , 535 , 537 , 538 , 539 , 540 , 541 , 542 , 543 , 544 , 546 , 547 , 548 , 549 , 550 , 551 , 552 , 553 , 554 , 555 , 556 , 557 , 558 , 559 , 560 , 561 , 562 , 564 , 565 , 566 , 567 , 568 , 569 , 570 , 571 , 572 , 573 , 574 , 575 , 576 , 577 , 578 , 579 , 580 , 581 , 582 , 583 ) , western blotting ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 59 , 61 , 62 , 63 , 64 , 65 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 102 , 103 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 145 , 146 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 165 , 167 , 169 , 170 , 171 , 175 , 176 , 177 , 178 , 180 , 181 , 182 , 184 , 185 , 186 , 188 , 190 , 191 , 192 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 , 213 , 214 , 215 , 216 , 217 , 219 , 220 , 221 , 222 , 223 , 224 , 225 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 235 , 236 , 237 , 239 , 240 , 241 , 242 , 243 , 244 , 245 , 246 , 247 , 249 , 250 , 251 , 252 , 253 , 254 , 256 , 257 , 258 , 259 , 260 , 261 , 263 , 264 , 265 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , 278 , 279 , 281 , 282 , 283 , 284 , 285 , 287 , 288 , 289 , 290 , 291 , 292 , 294 , 295 , 296 , 299 , 300 , 302 , 303 , 304 , 305 , 306 , 307 , 308 , 310 , 311 , 312 , 313 , 314 , 315 , 316 , 317 , 318 , 319 , 320 , 321 , 323 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 334 , 335 , 336 , 337 , 338 , 339 , 340 , 341 , 342 , 343 , 344 , 345 , 346 , 347 , 348 , 349 , 350 , 351 , 352 , 353 , 354 , 355 , 356 , 357 , 358 , 359 , 360 , 361 , 362 , 363 , 364 , 365 , 366 , 367 , 368 , 369 , 370 , 371 , 372 , 373 , 374 , 376 , 377 , 378 , 379 , 380 , 381 , 382 , 383 , 384 , 385 , 386 , 388 , 389 , 390 , 391 , 393 , 394 , 395 , 396 , 397 , 398 , 399 , 401 , 402 , 403 , 404 , 405 , 406 , 407 , 408 , 409 , 410 , 411 , 412 , 413 , 414 , 415 , 416 , 418 , 419 , 420 , 421 , 422 , 423 , 425 , 426 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 434 , 435 , 436 , 437 , 440 , 441 , 442 , 443 , 444 , 446 , 447 , 448 , 449 , 450 , 451 , 452 , 453 , 454 , 455 , 456 , 457 , 458 , 459 , 460 , 461 , 462 , 463 , 465 , 466 , 469 , 470 , 472 , 473 , 474 , 475 , 477 , 483 , 487 , 493 , 494 , 497 , 499 , 500 , 501 , 502 , 505 , 506 , 507 , 509 , 510 , 511 , 513 , 514 , 516 , 519 , 520 , 523 , 525 , 526 , 530 , 532 , 533 , 537 , 538 , 541 , 543 , 544 , 546 , 547 , 548 , 549 , 551 , 555 , 556 , 557 , 559 , 560 , 561 , 562 , 565 , 566 , 569 , 572 , 576 , 578 , 579 , 580 , 581 , 582 , 583 )

Alzheimer's disease ( 190 , 292 ) , bone cancer ( 47 , 290 ) , Ewing's sarcoma ( 47 ) , brain cancer ( 373 , 385 ) , glioblastoma ( 373 , 385 ) , glioma ( 149 , 373 , 385 ) , breast cancer ( 10 , 35 , 96 , 122 , 132 , 146 , 193 , 201 , 368 , 384 , 390 , 431 , 578 ) , breast adenocarcinoma ( 122 , 132 ) , breast ductal carcinoma ( 132 ) , breast cancer, triple negative ( 35 , 122 , 132 ) , cervical cancer ( 261 , 547 ) , cervical adenocarcinoma ( 547 ) , cervical squamous cell carcinoma ( 261 ) , colorectal cancer ( 46 , 290 , 333 , 432 , 532 ) , colorectal carcinoma ( 46 , 290 , 333 , 432 , 532 ) , endometrial cancer ( 469 ) , endometrial adenocarcinoma ( 469 ) , esophageal cancer ( 89 ) , esophageal carcinoma ( 89 ) , hypopharyngeal cancer ( 61 ) , kidney cancer ( 244 ) , leukemia ( 51 , 82 , 120 , 170 , 246 , 265 , 304 ) , acute myelogenous leukemia ( 51 , 82 , 170 ) , acute monoblastic leukemia (M5a) or acute monocytic leukemia (M5b) ( 51 ) , chronic lymphocytic leukemia ( 120 ) , chronic myelogenous leukemia ( 51 , 265 ) , T cell leukemia ( 246 ) , liver cancer ( 26 , 42 , 154 , 182 , 212 , 355 , 386 ) , hepatocellular carcinoma ( 212 ) , lung cancer ( 54 , 333 , 418 , 452 , 497 ) , mesothelioma ( 497 ) , non-small cell lung cancer ( 54 , 333 , 418 ) , non-small cell lung adenocarcinoma ( 54 ) , lymphoma ( 51 , 67 , 69 , 72 , 102 , 495 , 550 ) , anaplastic large cell lymphoma ( 72 ) , B cell lymphoma ( 67 , 69 , 550 ) , T cell lymphoma ( 102 , 495 ) , neuroblastoma ( 43 , 65 , 99 , 148 , 204 , 222 , 236 , 305 , 525 , 551 ) , oropharyngeal cancer ( 56 ) , squamous cell carcinoma of the oropharynx ( 56 ) , ovarian cancer ( 443 ) , pancreatic cancer ( 309 , 333 , 398 ) , pancreatic carcinoma ( 333 , 398 ) , multiple myeloma ( 267 , 543 ) , prostate cancer ( 67 , 330 , 380 ) , melanoma skin cancer ( 2 , 75 , 171 , 506 ) , fibrosarcoma of soft tissue ( 543 , 566 ) , cancer, squamous cell carcinoma ( 89 ) , diabetes mellitus ( 390 , 460 ) , type 2 diabetes ( 184 , 349 , 390 , 460 ) , Huntington's disease ( 241 ) , Lafora disease ( 362 ) , Duchenne muscular dystrophy ( 194 ) , schizophrenia ( 523 )

'3T3-L1, differentiated' (adipocyte) ( 98 , 217 , 255 ) , 'blood, plasma' ( 38 ) , 'brain, caudate-putamen' ( 161 ) , 'brain, cerebral cortex' ( 3 , 53 , 117 , 184 , 236 , 249 , 344 , 473 , 516 , 523 , 562 ) , 'brain, embryonic' ( 424 ) , 'brain, embryonic' [BAG1 (mouse)] ( 481 ) , 'brain, hippocampus' ( 3 , 20 , 53 , 79 , 143 , 184 , 236 , 249 , 350 , 433 , 473 ) , 'brain, hippocampus' [APP (human), genetic knockin] ( 292 ) , 'brain, hippocampus, CA1 region' ( 138 ) , 'brain, hypothalamus' ( 57 ) , 'brain, nucleus accumbens' ( 205 ) , 'brain, striatum' ( 241 , 473 , 484 , 524 ) , 'fat, brown'-'fat, brown' ( 314 , 338 ) , 'heart, embryo' ( 156 ) , 'liver, fetal' ( 463 ) , 'macrophage, alveolar' ( 7 ) , 'muscle, skeletal' ( 4 , 12 , 24 , 40 , 66 , 73 , 86 , 141 , 153 , 176 , 185 , 186 , 240 , 252 , 303 , 319 , 338 , 369 , 372 , 377 , 394 , 402 , 404 , 405 , 447 , 496 , 510 , 513 , 529 ) , 'muscle, skeletal' [APPL (human), homozygous knockout] ( 233 ) , 'muscle, skeletal' [DNAPK (mouse), homozygous knockout] ( 391 ) , 'muscle, skeletal' [genetic knockin] ( 233 ) , 'muscle, skeletal' [RICTOR (mouse), homozygous knockout] ( 366 , 413 ) , 'muscle, smooth'-pulmonary artery ( 55 ) , 'neuron, cortical' ( 22 , 129 , 268 , 361 , 414 ) , 'neuron, cortical'-brain ( 204 , 260 , 486 ) , 'neuron, cortical'-brain [NYAP2 (mouse), homozygous knockout] ( 272 ) , 'neuron, hippocampal' ( 268 ) , 'neuron, striatal' ( 181 ) , 'neuron, striatal'-brain ( 471 ) , 'neuron, superior cervical ganglion' ( 396 ) , 'renal, podocyte' ( 258 , 332 ) , 'stem, embryonic' ( 402 ) , 'stem, mesenchymal' ( 34 , 274 ) , 'stem, neural' ( 21 , 180 ) , 1205Lu (melanocyte) ( 2 ) , 293 (epithelial) ( 94 , 128 , 198 , 278 , 315 , 327 , 348 , 364 , 373 , 384 , 419 , 475 , 486 , 488 , 535 , 583 ) , 293E (epithelial) ( 432 ) , 32D (myeloid) ( 311 ) , 3T3 (fibroblast) [INSR (human)] ( 447 ) , 3T3 (fibroblast) [INSR (mouse), transfection] ( 383 ) , 3T3 (fibroblast) [SHP-2 (mouse), homozygous knockout] ( 485 , 494 , 497 , 501 , 504 , 541 , 546 , 549 , 554 , 565 , 571 , 573 , 574 , 575 ) , 3T3 (fibroblast) [Src (human)] ( 452 ) , 3T3 (fibroblast) ( 25 , 157 , 287 , 316 , 336 , 357 , 371 , 374 , 383 , 418 , 431 , 483 , 547 , 548 , 560 , 561 ) , 3T3-L1 (fibroblast) ( 6 , 84 , 144 , 151 , 169 , 296 , 346 , 347 , 351 , 399 , 426 , 428 , 440 , 447 , 460 , 477 , 556 ) , 4T1 (breast cell) ( 122 , 368 , 578 ) , 786-O (renal) ( 244 ) , A-375 (melanocyte) ( 110 ) , A2058 (keratinocyte) ( 75 ) , A375 (melanocyte) ( 75 ) , A431 (epithelial) ( 333 ) , A549 (pulmonary) ( 54 , 333 , 418 ) , adipocyte ( 444 ) , adipocyte [F2RL1 (mouse), homozygous knockout] ( 323 ) , adipocyte [N-CoR1 (mouse), homozygous knockout] ( 275 ) , adipocyte-adipose tissue ( 239 ) , adipocyte-adipose tissue [N-CoR1 (mouse), homozygous knockout] ( 275 ) , adipose tissue ( 13 , 26 , 52 , 71 , 86 , 92 , 98 , 116 , 136 , 141 , 142 , 144 , 153 , 214 , 240 , 304 , 402 , 447 , 499 , 508 ) , adipose tissue [DNAPK (mouse), homozygous knockout] ( 391 ) , adipose tissue [F2RL1 (mouse), homozygous knockout] ( 323 ) , adipose tissue [p70S6K (mouse), homozygous knockout] ( 507 ) , adipose tissue [RICTOR (mouse), homozygous knockout] ( 366 ) , AE7 ( 435 ) , alpha-TC6 (pancreatic) ( 145 ) , alphaT3-1 (pituitary cell) ( 245 ) , AML12 (hepatic) ( 10 , 25 , 114 , 137 ) , AML3080 ( 51 ) , AML3179 ( 51 ) , AML3220 ( 51 ) , aorta ( 63 , 434 ) , artery ( 407 ) , AS-B634 ( 146 ) , astrocyte-'brain, striatum' ( 515 ) , AV12 ('neuron, neostriatal') ( 511 ) , B lymphocyte ( 45 , 81 , 93 , 107 , 120 , 158 , 461 ) , B lymphocyte [BCAP (mouse), homozygous knockout] ( 412 ) , B lymphocyte [CD19 (mouse), homozygous knockout] ( 412 ) , B lymphocyte-spleen ( 234 , 279 , 343 ) , B lymphocyte-spleen [PTEN (mouse), transgenic] ( 358 ) , B16F10 ( 171 ) , B9 (fibroblast) ( 543 ) , BAEC (endothelial) ( 479 ) , BaF3 ('B lymphocyte, precursor') [EGFR (human)] ( 452 ) , BaF3 ('B lymphocyte, precursor') ( 167 , 256 , 339 , 353 , 383 , 425 , 429 , 449 , 488 , 518 , 569 ) , BALB/MK (keratinocyte) ( 582 ) , BE (melanocyte) ( 506 ) , beta TC3 (pancreatic) ( 398 ) , beta-pancreas ( 453 ) , beta-pancreas [INSR (mouse), transgenic] ( 334 ) , BLMVEC (endothelial) ( 520 ) , BMMC (mast) ( 318 , 579 ) , bone marrow ( 34 , 51 , 80 , 121 , 234 , 449 , 509 ) , brain ( 105 , 123 , 126 , 243 , 262 , 406 , 466 ) , brain [CDK5R1 (mouse)] ( 406 ) , brain [laforin (mouse), homozygous knockout] ( 362 ) , brain [NYAP2 (mouse), homozygous knockout] ( 272 ) , breast [PDK1 (mouse), homozygous knockout] ( 201 ) , breast cell ( 193 ) , BT-474 (breast cell) ( 96 ) , BT-549 (breast cell) ( 35 , 122 ) , C141 (epidermal) ( 563 ) , C166 ( 159 ) , C2C12 (myoblast) [LIN28A (mouse), transfection] ( 288 ) , C2C12 (myoblast) ( 4 , 24 , 74 , 106 , 108 , 111 , 119 , 134 , 135 , 155 , 208 , 240 , 282 , 283 , 363 , 411 , 415 , 423 , 436 , 493 , 577 ) , C3H10T1/2 (fibroblast) ( 403 ) , C666-1 ( 61 ) , Calu-1 (squamous) ( 418 ) , CaSki (cervical) ( 261 ) , CD4+ (T lymphocyte) ( 49 , 91 , 102 , 104 , 130 , 131 , 179 , 301 ) , CD8+ (T lymphocyte) ( 11 , 48 , 49 , 78 , 133 , 179 ) , CEF ( 570 ) , CHO (fibroblast) [Tau iso8 (human)] ( 465 ) , CHO (fibroblast) ( 156 , 203 , 576 ) , CMT-93 (intestinal) ( 532 ) , CNE-2 (squamous) ( 56 ) , CNE1 ( 61 ) , colon ( 29 , 46 , 147 , 191 ) , COS (fibroblast) ( 256 , 362 , 383 , 488 , 539 , 552 ) , COS7 (fibroblast) ( 264 ) , CTL-EN (T lymphocyte) ( 416 ) , CTLL-2 (T lymphocyte) ( 557 ) , D3 mES (stem) ( 152 ) , diaphragm ( 194 ) , DLD1 (intestinal) ( 333 ) , DT40 (B lymphocyte) ( 69 ) , DU 145 (prostate cell) ( 67 , 380 ) , E14tg2a ('stem, embryonic') ( 209 , 505 ) , EL-4 (T lymphocyte) ( 102 ) , embryo ( 262 , 463 ) , endothelial ( 335 , 393 ) , epithelial ( 397 ) , epithelial-lens ( 430 ) , ES (stem) ( 219 , 294 ) , ESC ( 103 ) , ESC-CMs ('stem, embryonic') ( 152 ) , F9 (testicular) ( 552 ) , Fao (hepatic) ( 386 ) , fat ( 257 ) , FDCP-1 (myeloid) ( 489 ) , fibroblast ( 115 , 147 , 195 ) , fibroblast-embryo [BAG1 (mouse)] ( 481 ) , FL ( 304 ) , G361 (melanocyte) ( 542 ) , gastrointestinal tract ( 39 ) , GD25 (fibroblast) ( 512 , 538 ) , GL261 (glial) ( 68 ) , GSCs (glial) ( 149 ) , GT1-7 (neuron) ( 464 ) , H157 ( 54 ) , H9c2 (myoblast) ( 85 , 87 , 447 ) , HaCaT (keratinocyte) ( 196 ) , HBMEC (endothelial) ( 41 ) , HCC1937 (breast cell) ( 132 ) , HCC38 (breast cell) ( 132 ) , HCCLM3 (hepatic) ( 212 ) , HCT116 (intestinal) ( 46 , 290 ) , HCT15 (intestinal) ( 333 ) , heart ( 13 , 36 , 97 , 109 , 123 , 150 , 165 , 231 , 319 , 331 , 402 , 408 , 420 , 447 , 470 , 528 ) , heart [AMPKA2 (mouse), homozygous knockout] ( 389 ) , heart [DNAPK (human), transfection] ( 391 ) , HEI-OC1 ( 178 ) , HEK293T (epithelial) ( 31 , 67 , 91 , 123 , 129 , 203 , 232 , 246 , 252 , 260 , 270 , 320 , 321 , 367 , 432 , 580 ) , HeLa (cervical) ( 67 , 253 , 277 , 290 , 310 , 327 , 333 , 384 , 432 , 488 , 507 ) , HeLa S3 (cervical) ( 547 ) , hematopoietic stem cells ( 15 , 286 ) , hepatocyte ( 10 , 112 , 114 , 315 , 355 ) , hepatocyte-liver ( 137 , 254 , 259 , 313 , 376 , 453 ) , hepatocyte-liver [eIF2-alpha (mouse), homozygous knockout] ( 386 ) , hepatocyte-liver [TSC1 (mouse), homozygous knockout] ( 295 ) , HepG2 (hepatic) ( 26 , 42 , 154 , 182 , 355 , 583 ) , HT-29 (intestinal) ( 432 ) , HUVEC (endothelial) ( 16 , 29 , 63 , 393 , 444 ) , IC2 (mast) ( 530 ) , intestine ( 210 ) , Ishikawa (endometrial) ( 469 ) , J558L (B lymphocyte) ( 267 ) , J774 (macrophage) ( 559 ) , JB (epithelial) ( 500 , 540 ) , Jurkat (T lymphocyte) ( 388 ) , Jurkat E6-1 (T lymphocyte) ( 246 ) , K562 (erythroid) ( 51 , 265 ) , keratinocyte ( 474 ) , keratinocyte-skin ( 468 , 472 ) , keratinocyte-skin [IGF1 (mouse)] ( 475 ) , kidney ( 123 , 164 ) , Kyse180 (esophageal) ( 89 ) , Kyse30 (esophageal) ( 89 ) , L6 (myoblast) ( 12 , 33 , 336 ) , liver ( 1 , 5 , 10 , 28 , 38 , 42 , 51 , 70 , 71 , 88 , 92 , 114 , 116 , 123 , 124 , 136 , 139 , 141 , 142 , 153 , 154 , 163 , 175 , 182 , 214 , 240 , 257 , 262 , 278 , 285 , 300 , 304 , 312 , 315 , 321 , 338 , 352 , 382 , 390 , 402 , 447 , 510 , 558 ) , liver [DNAPK (mouse), homozygous knockout] ( 391 ) , liver [p70S6K (mouse), homozygous knockout] ( 507 ) , liver [RICTOR (mouse), homozygous knockout] ( 366 ) , LNCaP (prostate cell) ( 67 ) , LU-NB-1 ( 125 ) , lung ( 17 , 38 , 100 , 122 , 123 , 162 , 170 , 177 , 393 , 496 ) , lymph node ( 107 ) , lymphocyte ( 19 , 130 , 202 , 207 , 523 ) , lymphocyte-spleen ( 104 , 192 , 206 , 211 ) , lymphocyte-spleen [p53 (mouse), transfection] ( 395 ) , M059J (glial) ( 373 , 421 ) , M1 (myeloid) ( 265 ) , M12 (B lymphocyte) ( 67 ) , M2-10B4 ( 220 ) , macrophage ( 17 ) , macrophage-bone marrow ( 7 , 37 , 76 , 94 , 118 , 128 , 142 , 190 , 199 , 216 , 427 , 442 , 533 ) , macrophage-peritoneum ( 169 , 365 ) , mammary gland ( 122 , 197 ) , mast-bone marrow ( 215 , 458 , 504 ) , mast-bone marrow [SHP-2 (mouse), homozygous knockout] ( 360 ) , MCF-7 (breast cell) ( 10 , 35 , 122 , 146 , 384 , 431 ) , MCF10A1 (epithelial) ( 14 ) , MDA-MB-231 (breast cell) ( 122 ) , MDA-MB-453 (breast cell) ( 390 ) , MDA-MB-468 (breast cell) ( 122 , 132 ) , MEC1 (B lymphocyte) ( 120 ) , MEF (fibroblast) [Akt1 (mouse), heterozygous knockout] ( 354 ) , MEF (fibroblast) [Akt1 (mouse), homozygous knockout] ( 289 ) , MEF (fibroblast) [Akt2 (mouse), homozygous knockout] ( 354 ) , MEF (fibroblast) [BAG4 (mouse), homozygous knockout] ( 291 ) , MEF (fibroblast) [DNAPK (mouse), homozygous knockout] ( 391 ) , MEF (fibroblast) [EIF4E (mouse), genetic knockin] ( 330 ) , MEF (fibroblast) [GADD34 (human)] ( 419 ) , MEF (fibroblast) [IGF1R (mouse)] ( 480 , 492 , 502 ) , MEF (fibroblast) [LKB1 (mouse)] ( 519 ) , MEF (fibroblast) [mTOR (mouse), homozygous knockout] ( 384 ) , MEF (fibroblast) [NRas (mouse), homozygous knockout] ( 581 ) , MEF (fibroblast) [PDGFRA (mouse), genetic knockin] ( 381 ) , MEF (fibroblast) [PKR (mouse), homozygous knockout] ( 349 ) , MEF (fibroblast) [RICTOR (human), homozygous knockout] ( 327 ) , MEF (fibroblast) [Sin1 (mouse), homozygous knockout] ( 337 , 378 ) , MEF (fibroblast) [TMEM55B (mouse), homozygous knockout] ( 370 ) , MEF (fibroblast) ( 90 , 105 , 106 , 123 , 128 , 182 , 198 , 240 , 244 , 247 , 253 , 263 , 264 , 266 , 270 , 273 , 276 , 308 , 310 , 324 , 325 , 328 , 340 , 341 , 346 , 348 , 359 , 372 , 373 , 379 , 385 , 401 , 403 , 418 , 421 , 422 , 432 , 440 , 446 , 448 , 454 , 455 , 456 , 457 , 459 , 462 , 537 ) , melanocyte-skin ( 110 ) , MES (pulmonary) ( 497 ) , mesenchymal ( 156 ) , MeWo (melanocyte) ( 75 ) , MH-S (macrophage) ( 160 ) , MHCC97-L (hepatic) ( 212 ) , MIA PaCa-2 (pancreatic) ( 333 ) , microglia ( 62 , 441 ) , mIMCD-3 (epithelial) ( 555 ) , MLE12 (epithelial) ( 17 ) , mLEC (epithelial) ( 302 ) , MLO-Y4 (osteoblast) ( 243 ) , MMC (mesangial) ( 438 ) , MMTV-PyMT (breast cell) [JNK2 (mouse), homozygous knockout] ( 306 ) , MPC-11 (B lymphocyte) ( 543 ) , MPC5 ( 18 ) , MS1 (endothelial) ( 493 ) , muscle ( 33 , 50 , 71 , 83 , 92 , 116 , 142 , 214 , 304 , 460 ) , muscle [laforin (mouse), homozygous knockout] ( 362 ) , muscle [p70S6K (mouse), homozygous knockout] ( 507 ) , MV4-11 (macrophage) ( 51 ) , MVT-1 (epithelial) ( 193 ) , myeloid ( 76 , 442 ) , myoblast ( 405 , 514 ) , myocyte-heart ( 87 , 109 , 152 , 230 , 235 , 250 , 307 , 415 , 437 , 572 ) , myotubes ( 74 , 134 ) , N1E-115 (neuron) ( 204 , 525 ) , nasopharyngeal ( 61 ) , NCI-H1299 (pulmonary) ( 333 ) , NCI-H157 (pulmonary) ( 418 ) , Neuro-2a (neuron) ( 43 , 65 , 99 , 148 , 222 , 305 , 551 ) , neuron ( 126 ) , neuron-'brain, cerebral cortex' ( 544 ) , neuron-'brain, cerebral cortex' [STAT1 (mouse), homozygous knockout] ( 544 ) , neuron-'brain, hippocampus' ( 222 ) , neuron-brain ( 58 ) , neuron-dorsal root ganglia ( 271 ) , neutrophil ( 121 , 237 , 269 ) , NHDF (fibroblast) ( 247 ) , NMuMG (epithelial) ( 221 , 578 ) , NPC (neural crest) ( 117 ) , oocyte ( 113 ) , osteoclast ( 23 , 442 ) , ovarian ( 443 ) , ovary ( 113 ) , pancreatic ( 309 ) , pancreatic islet ( 27 , 59 ) , PaTu (pancreatic) ( 333 ) , PC-12 (chromaffin) ( 490 ) , PC3 (prostate cell) ( 67 , 380 ) , penis ( 522 ) , platelet ( 95 , 140 ) , platelet-blood ( 188 , 284 , 521 ) , preadipocyte ( 444 ) , preosteoclast ( 491 ) , prostate ( 38 , 44 , 67 , 354 , 397 ) , prostate [homozygous knockout] ( 299 ) , R1 ('stem, embryonic') ( 77 ) , Rat1 (fibroblast) ( 421 , 459 ) , RAW 264 (macrophage) ( 534 ) , RAW 264.7 (macrophage) ( 101 , 128 , 320 ) , RIE (epithelial) ( 459 ) , RWPE1 (prostate cell) ( 127 ) , Sbcl2 (melanocyte) ( 2 ) , SCC16-5 (fibroblast) ( 567 ) , sertoli-testis ( 200 ) , SF9 ( 571 ) , SH-SY5Y (neural crest) ( 43 ) , SiHa (squamous) ( 261 ) , SJSA-1 (bone cell) ( 47 ) , SK-MEL5 (melanocyte) ( 75 ) , skin ( 196 ) , SKNSH (neural crest) ( 236 ) , SKOV-3 (ovarian) ( 443 ) , SN4741 (neuron) ( 526 ) , spermatozoa ( 64 ) , spinal cord ( 180 ) , spleen ( 38 , 123 , 234 , 509 ) , stem ( 32 ) , STHdh ('neuron, striatal') ( 30 ) , SV40 ( 564 ) , SW480 (intestinal) ( 46 ) , SYF (fibroblast) ( 329 ) , T lymphocyte-blood ( 301 , 527 ) , T lymphocyte-lymph node ( 356 ) , T lymphocyte-lymph node [PKCT (mouse), homozygous knockout] ( 326 ) , T lymphocyte-spleen ( 234 , 242 , 317 , 409 , 435 , 451 ) , T lymphocyte-spleen [PKCT (mouse), homozygous knockout] ( 326 ) , T lymphocyte-thymus ( 301 , 495 ) , thoracic aorta ( 450 , 487 ) , THP1 (myeloid) ( 82 , 170 ) , thymocyte ( 60 , 130 , 345 ) , thymocyte [CBL (mouse), homozygous knockout] ( 342 ) , thyroid [Akt1 (mouse), homozygous knockout] ( 281 ) , TS (lymphocyte) ( 72 ) , U-251 MG (glial) ( 385 ) , U-937 (myeloid) ( 51 ) , U2OS (bone cell) [GR (human)] ( 488 ) , U2OS (bone cell) ( 290 ) , UOK-101 (renal) ( 244 ) , uterus ( 90 , 469 , 482 ) , VSMC-aorta ( 503 ) , WEHI-164 (fibroblast) ( 566 ) , WEHI-231 (B lymphocyte) ( 550 ) , WM2664 (melanocyte) ( 2 )

14-3-3 zeta (mouse) ( 367 ) , ABCB10 (human) ( 137 ) , ACVR2B (mouse) ( 436 ) , adiponectin (human) ( 34 ) , ADRB1 (mouse) ( 314 ) , AKAP1 (human) ( 100 ) , Akt1 (human) ( 56 , 397 ) , Akt1 (mouse) ( 213 , 281 , 419 , 579 ) , Akt2 (mouse) ( 285 , 345 ) , Akt3 (mouse) ( 284 ) , ALK (human) ( 339 ) , AML2 (human) ( 49 ) , AMPKA1 (human) ( 114 , 182 ) , AMPKA2 (human) ( 114 , 182 ) , AMPKA2 (mouse) ( 389 ) , APP (human) ( 3 ) , APP (mouse) ( 236 ) , APPBP2 (human) ( 70 ) , APPL (human) ( 240 ) , APPL2 (human) ( 233 ) , AREG (human) ( 15 ) , ARRB1 (human) ( 124 ) , AS160 (human) ( 319 ) , ATF6A (mouse) ( 386 ) , ATG5 (mouse) ( 157 ) , ATG7 (human) ( 41 ) , BAFF (mouse) ( 461 ) , BAG1 (mouse) ( 481 ) , BAG4 (mouse) ( 291 ) , BCAP (mouse) ( 412 ) , BCR-ABL1 (human) ( 452 ) , BIRC4BP (human) ( 31 ) , BLVRB (human) ( 12 ) , BLVRB (mouse) ( 12 ) , BRCA1 (human) ( 297 ) , BRCA2 (human) ( 15 ) , Brk (human) ( 329 ) , Btk (mouse) ( 579 ) , C3aR (mouse) ( 409 ) , C5aR (mouse) ( 409 ) , Calnexin (human) ( 22 ) , CASP1 (mouse) ( 304 ) , caveolin-1 (mouse) ( 294 ) , CBFB (human) ( 49 ) , CBL (mouse) ( 342 ) , Cbl-b (human) ( 130 ) , CBP (human) ( 72 ) , CD151 (mouse) ( 215 ) , CD19 (mouse) ( 412 ) , CD248 (human) ( 47 ) , CD37 (human) ( 118 ) , CDC42 iso1 (mouse) ( 472 ) , CDH1 (human) ( 149 ) , CDH2 (mouse) ( 344 ) , CDK5 (mouse) ( 406 ) , CDK5R1 (mouse) ( 406 ) , CDKL5 (human) ( 20 ) , CEP55 (human) ( 105 ) , CIDEC (human) ( 71 ) , CKM (mouse) ( 24 ) , CLK2 (human) ( 315 ) , CMIP (mouse) ( 258 ) , coronin 1A (human) ( 104 ) , CREB3L3 (human) ( 136 ) , CTH (human) ( 61 , 101 ) , CTU2 (human) ( 76 ) , CXCL12 (human) ( 120 ) , CXCL13 (human) ( 120 ) , CYP4F22 (human) ( 88 ) , DDIT4 (mouse) ( 161 ) , DICER1 (mouse) ( 211 ) , DKK3 (mouse) ( 24 ) , DLK2 (human) ( 23 ) , DNAPK (mouse) ( 373 , 391 ) , DRP1 (human) ( 119 ) , dystrophin (human) ( 106 ) , EGFR (human) ( 68 , 149 ) , EIF4E (mouse) ( 330 ) , ELP3 (human) ( 76 ) , ENHO (mouse) ( 163 ) , ERK5 (human) ( 520 ) , F2RL1 (mouse) ( 323 ) , FAK (mouse) ( 335 ) , FAM105B (human) ( 175 ) , FGFR1 (human) ( 425 ) , FGFR4 (human) ( 72 ) , FOXO1A (human) ( 120 , 340 ) , FOXO1A (mouse) ( 244 , 340 , 444 ) , Fyn (mouse) ( 356 ) , G-alpha(s) (human) ( 144 ) , GAB1 (human) ( 120 ) , GAB2 (mouse) ( 458 ) , GADD34 (human) ( 419 ) , GCN2 (mouse) ( 289 ) , GGPS1 (human) ( 74 ) , GILZ (human) ( 265 ) , GLRX1 (mouse) ( 430 ) , Gm364 (mouse) ( 113 ) , GPM6A (human) ( 222 ) , GPX1 (mouse) ( 510 ) , GRB10 (human) ( 239 , 256 ) , GRB10 (mouse) ( 218 ) , HDAC6 (human) ( 72 ) , HER3 (human) ( 156 ) , Huntingtin (mouse) ( 161 , 524 ) , ICMT (mouse) ( 537 ) , IFI16 (mouse) ( 410 ) , IFITM3 (human) ( 158 ) , IFITM3 (rat) ( 158 ) , IGF1R (mouse) ( 436 , 517 ) , IGF2BP2 (mouse) ( 185 ) , IKKA (human) ( 264 ) , IKKA (mouse) ( 461 ) , IKKB (human) ( 264 ) , IKKG (human) ( 264 ) , IKKG (mouse) ( 467 ) , IL6R (human) ( 149 ) , IL8RA (human) ( 32 ) , IL8RB (human) ( 32 ) , ILK (human) ( 274 ) , ILK (mouse) ( 191 , 405 ) , INPP5B (human) ( 69 ) , IRF3 (human) ( 88 ) , IRS1 (human) ( 74 , 145 , 235 , 453 ) , IRS1 (mouse) ( 453 ) , IRS2 (human) ( 145 , 235 ) , IRS2 (mouse) ( 453 ) , IRX3 (mouse) ( 116 ) , ITGA9 (human) ( 449 ) , ITGB1 (human) ( 538 ) , ITGB1 (mouse) ( 377 ) , ITGB3 (mouse) ( 171 ) , JAK2 (mouse) ( 569 ) , JIP1 (mouse) ( 508 ) , JNK1 (mouse) ( 307 ) , JNK2 (mouse) ( 306 ) , K17 (mouse) ( 468 ) , KOR-1 (human) ( 89 ) , KRas (human) ( 123 ) , KRas (mouse) ( 456 , 582 ) , KYNU (human) ( 11 ) , LAB (mouse) ( 451 ) , laforin (mouse) ( 362 ) , LAMTOR1 (human) ( 341 ) , LAMTOR2 (mouse) ( 341 ) , LEF-1 (human) ( 78 ) , LIMS1 (human) ( 333 ) , LIMS1 (mouse) ( 333 ) , LIN28A (mouse) ( 288 ) , LIN28B (mouse) ( 288 ) , LKB1 (mouse) ( 404 ) , LPIN1 (mouse) ( 375 ) , LST8 (mouse) ( 448 ) , LYN (human) ( 107 ) , LYN (mouse) ( 579 ) , MARCH3 (mouse) ( 94 ) , MEK5 (human) ( 520 ) , MEKK4 (human) ( 72 ) , Met (human) ( 149 ) , Met (mouse) ( 171 ) , METRNL (mouse) ( 16 ) , METTL3 (human) ( 103 ) , MFGE8 (human) ( 4 ) , Mnk1 (mouse) ( 418 ) , Mnk2 (mouse) ( 418 ) , MT1 (mouse) ( 470 ) , MTHFD2 (human) ( 37 ) , mTOR (human) ( 128 , 140 ) , mTOR (mouse) ( 200 , 283 ) , Musashi-1 (mouse) ( 210 ) , MYD88 (human) ( 365 ) , MYD88 (mouse) ( 7 ) , N-CoR1 (mouse) ( 275 ) , NDR1 (human) ( 42 ) , NF1 (mouse) ( 446 ) , NFkB-p100 (mouse) ( 198 ) , NFkB-p65 (human) ( 124 ) , NLRP3 (mouse) ( 304 ) , nNOS (human) ( 154 ) , NOX4 (human) ( 147 ) , NPM1 (human) ( 339 ) , NRas (mouse) ( 581 ) , NYAP2 (mouse) ( 272 ) , OCRL (human) ( 69 ) , P38A (mouse) ( 328 ) , p53 (mouse) ( 225 ) , p70S6K (mouse) ( 283 ) , PAG (rat) ( 401 ) , PAK1 (human) ( 160 ) , PAK4 (human) ( 28 ) , PCYT2 (human) ( 131 ) , PD-L1 (human) ( 121 ) , PDGFRA (human) ( 149 ) , PDGFRA (mouse) ( 381 ) , PDK1 (human) ( 91 ) , PDK1 (mouse) ( 201 , 402 ) , PECAM-1 (human) ( 29 ) , perilipin 5 (human) ( 36 ) , PERK (mouse) ( 289 ) , PGGT1B (human) ( 74 ) , PGGT1B (mouse) ( 199 ) , PHB (human) ( 363 ) , PHLDA1 (human) ( 5 ) , PIERCE1 (human) ( 162 ) , PIK3C2A (mouse) ( 556 ) , PIK3CA (mouse) ( 273 ) , PIK3CG (human) ( 269 ) , PIK3R1 (human) ( 264 ) , PIKFYVE (human) ( 252 ) , PIKFYVE (mouse) ( 252 ) , Pim1 (human) ( 380 ) , PKCA (human) ( 326 , 474 ) , PKCA (mouse) ( 393 ) , PKCD (human) ( 474 ) , PKCE (human) ( 474 ) , PKCI (mouse) ( 545 ) , PKCT (mouse) ( 407 ) , PKDCC (human) ( 95 ) , PKR (mouse) ( 349 ) , PLCB2 (human) ( 269 ) , PPM1K (human) ( 48 ) , PPP1CA (human) ( 43 ) , PPP1CC (human) ( 43 ) , PPP2R1B (human) ( 88 ) , PPP2R5B (human) ( 315 ) , PPP2R5B (mouse) ( 374 ) , Prl2a1 (mouse) ( 51 ) , PSEN1 (human) ( 3 ) , PSEN1 (mouse) ( 236 ) , PTEN (human) ( 25 , 38 , 44 , 58 , 60 , 90 , 177 ) , PTEN (mouse) ( 2 , 204 , 213 , 219 , 223 , 224 , 299 , 358 , 379 , 385 , 466 , 469 ) , PTGER3 (mouse) ( 318 ) , PTGER4 (mouse) ( 332 ) , PTN (human) ( 21 ) , PTPRZ1 (human) ( 21 ) , PYCARD (mouse) ( 304 ) , RABGGTA (human) ( 74 ) , Raptor (human) ( 58 ) , Raptor (mouse) ( 164 , 283 , 318 , 457 ) , RASAL2 (human) ( 132 ) , Rb (mouse) ( 225 ) , RBPJ (mouse) ( 228 ) , Ret (human) ( 396 ) , RHEB (mouse) ( 283 ) , RhoGDI alpha (human) ( 33 ) , RIC8B (human) ( 76 ) , RICTOR (human) ( 128 , 152 , 197 , 278 , 348 , 359 , 366 ) , RICTOR (mouse) ( 7 , 102 , 244 , 253 , 263 , 318 , 327 , 338 , 340 , 348 , 379 , 399 , 413 , 448 ) , RNF31 (human) ( 67 ) , ROCK1 (mouse) ( 369 ) , SCD (mouse) ( 499 ) , SESN2 (human) ( 182 ) , SGK1 (human) ( 114 ) , SGK1 (mouse) ( 242 ) , SH3BP2 (mouse) ( 442 ) , SHARPIN (human) ( 67 ) , SHC1 (mouse) ( 438 ) , SHP-2 (human) ( 300 ) , SHP-2 (mouse) ( 360 , 554 ) , SHPS1 (human) ( 118 ) , SIGLEC7 (mouse) ( 237 ) , SIK (human) ( 214 ) , Sin1 (human) ( 123 , 337 ) , Sin1 (mouse) ( 273 , 337 , 378 , 455 ) , SIRT1 (human) ( 278 ) , SIRT1 (mouse) ( 322 ) , SIRT7 (human) ( 122 ) , SIRT7 (mouse) ( 122 ) , SMO (mouse) ( 195 ) , SPHK1 (human) ( 313 ) , Src (human) ( 452 ) , SRR (human) ( 117 ) , STAT3 (human) ( 355 ) , SYAP1 (human) ( 23 ) , Syk (human) ( 62 ) , Syk (mouse) ( 579 ) , syndecan-4 (mouse) ( 393 ) , TBK1 (human) ( 93 , 128 ) , TBK1 (mouse) ( 320 , 456 ) , TCF7 (human) ( 78 ) , TCL1A (mouse) ( 580 ) , TDGF1 (mouse) ( 286 ) , TICAM1 (mouse) ( 7 ) , TLR2 (mouse) ( 7 ) , TMCC3 (human) ( 146 ) , TMEM55B (mouse) ( 370 ) , TNFAIP8 (human) ( 115 ) , TORC2 (mouse) ( 375 ) , TRB2 (human) ( 49 ) , TREM2 (mouse) ( 190 ) , TSC1 (mouse) ( 295 , 346 , 454 ) , TSC2 (human) ( 55 ) , TSC2 (mouse) ( 266 , 270 , 334 , 340 , 432 , 454 , 457 , 462 ) , TTC3 (human) ( 357 ) , UBC9 (human) ( 91 ) , UBXN2A (human) ( 46 ) , VAV3 (human) ( 81 ) , VEGF iso1 (human) ( 251 ) , WDR24 (human) ( 182 ) , WWTR1 (human) ( 74 ) , ZAP70 (human) ( 130 ) , ZBTB7B (human) ( 49 )

Akt1 (mouse) ( 89 , 583 ) , ILK (human) ( 533 ) , mTOR (human) ( 35 , 128 ) , P38A (mouse) ( 514 ) , PAK4 (human) ( 77 ) , PIK3C2A (human) ( 251 ) , PKCB (mouse) ( 504 )

Akt1 (mouse) ( 583 ) , mTOR (human) ( 128 , 182 , 265 ) , mTOR (mouse) ( 253 , 478 ) , Notch 2 (mouse) ( 113 ) , PAK4 (human) ( 77 ) , PKCA (mouse) ( 326 ) , TBK1 (human) ( 128 )

PHLPP (mouse) ( 301 ) , PHLPP2 (mouse) ( 301 ) , PPP2CA (human) ( 147 , 315 ) , PTEN (mouse) ( 37 , 67 , 571 )

cochlioquinone B derivative ( 160 ) , extracellular vesicles ( 26 ) , L-NPA ( 154 ) , #11a ( 126 ) , 1-butanol ( 490 ) , 3-PEHPC ( 74 ) , 4-HT ( 340 , 383 ) , 8,8'-bieckol ( 148 ) , 8-(3-chlorostyryl) caffeine ( 420 ) , 8-Rp-cAMP ( 431 ) , A-443654 ( 383 ) , acadesine ( 252 , 414 , 519 ) , acetic acid ( 157 ) , ACh ( 503 ) , actinomycin_D ( 549 ) , activin ( 543 ) , adiponectin ( 26 , 240 , 368 ) , ADP ( 95 , 140 ) , adriamycin ( 122 , 328 ) , AG1295 ( 55 ) , AG1433 ( 538 ) , AG1478 ( 490 ) , Akt-I-1 ( 383 ) , Akt_activator_compound_11 ( 316 ) , Akt_inhibitor_VIII ( 243 , 269 , 273 , 274 , 289 , 383 ) , Akt_inhibitor_X ( 250 ) , alloxan ( 87 ) , alloxazine ( 420 ) , alpelisib ( 128 , 182 ) , alpha-lipoic_acid ( 305 ) , AM251 ( 303 ) , amino_acid_starvation ( 448 ) , amino_acids ( 30 , 128 , 270 , 336 , 355 , 454 ) , amlexanox ( 42 , 128 ) , angiopoietin-1 ( 493 ) , angiopoietin-2 ( 493 ) , angiotensin_2 ( 258 , 322 , 450 ) , antibody ( 4 , 19 , 49 , 80 , 96 , 104 , 107 , 120 , 130 , 192 , 206 , 211 , 224 , 242 , 261 , 279 , 304 , 317 , 326 , 342 , 343 , 356 , 358 , 360 , 388 , 409 , 412 , 451 , 493 , 538 ) , antigenic stimulation ( 7 ) , apyrase ( 140 ) , arsenite ( 540 ) , AS252424 ( 318 ) , atorvastatin ( 420 ) , ATP ( 73 ) , axatomy ( 226 ) , AZD8055 ( 144 , 247 ) , bacterial infection ( 82 , 532 ) , BAPTA-AM ( 521 , 560 ) , BDNF ( 204 , 260 ) , BI-D1870 ( 356 ) , bicuculline ( 260 ) , bisindolylmaleimide ( 326 ) , bite-opening ( 165 ) , blood pressure ( 450 ) , BLU9931 ( 72 ) , BMS-536924 ( 30 ) , branched-chain amino acids deprivation ( 48 , 86 ) , BRD0705 ( 50 ) , bromocriptine ( 526 ) , butaprost ( 318 ) , butein ( 56 ) , BX795 ( 128 , 157 , 378 ) , BX912 ( 157 ) , C3aR_antagonist ( 409 ) , C5aR_antagonist ( 409 ) , calphostin_C ( 274 ) , calyculin_A ( 474 ) , canertinib ( 406 ) , cangrelor ( 521 ) , carboplatin ( 111 ) , CAS_227449-73-2 ( 256 ) , castration ( 299 ) , catalase ( 563 ) , CC260 ( 135 ) , Cell culture supernatent ( 29 ) , cell_adhesion ( 512 ) , cetuximab ( 15 ) , CF3CN ( 126 ) , CGRP ( 109 ) , CHIR99021 ( 72 ) , chloroquine ( 98 ) , chronic unpredictable stress ( 143 ) , ciclopirox_olamine ( 302 ) , cilengitide ( 171 ) , cisplatin ( 247 ) , CL316,243 ( 139 ) , clodronic_acid ( 142 ) , clonidine ( 503 ) , cochlioquinone B derivative (CoB1) ( 160 ) , cold_water_stress ( 433 ) , colforsin ( 332 , 492 , 573 ) , collagen ( 140 ) , Collagen related peptide ( 140 ) , compound 21 ( 13 ) , compound_C ( 92 , 114 ) , ConA ( 382 ) , conditioned medium ( 92 , 120 ) , copanlisib ( 157 ) , cpd22 ( 191 ) , CRP ( 439 ) , culturing_of_cells ( 268 ) , CXCL12 ( 550 ) , CXCL5 ( 372 ) , CXCL8 ( 32 ) , Cyasterone ( 17 ) , cyclic_stretch ( 332 ) , cycloheximide ( 266 , 325 , 549 ) , cysteine ( 117 ) , dabrafenib ( 75 ) , dactolisib ( 244 , 299 ) , dapagliflozin ( 164 ) , DEN ( 124 ) , Dendrobium officinale polysaccharide ( 18 ) , deoxygenation ( 129 ) , development ( 49 , 470 ) , dexamethasone ( 265 , 347 ) , DI-PHPB ( 236 ) , dieckol ( 148 ) , DNP ( 579 ) , doconexent ( 551 ) , DPCPX ( 420 ) , Dynasore ( 279 ) , eckol ( 148 ) , EDTA ( 493 ) , EGF ( 14 , 122 , 128 , 204 , 291 , 306 , 329 , 354 , 370 , 371 , 410 , 445 , 455 , 474 , 490 , 537 , 542 , 553 , 554 , 555 , 573 , 578 , 582 ) , EGTA ( 490 , 524 ) , eplerenone ( 194 ) , Epo ( 353 ) , estradiol ( 431 , 471 , 477 , 572 ) , ethanol ( 558 ) , ether ( 433 ) , etoposide ( 247 ) , exercise ( 86 , 143 , 238 , 404 , 405 ) , exercise training ( 40 , 235 ) , faslodex ( 477 ) , fasting ( 28 , 122 , 186 , 232 , 264 , 315 , 322 , 352 ) , FGF2 ( 393 , 455 , 474 , 479 , 553 ) , fibrinogen ( 237 ) , fibronectin ( 47 ) , fingolimod ( 241 ) , fluoxetine ( 143 ) , fMLP ( 269 ) , food deprivation ( 433 ) , fostriecin ( 484 ) , free_fatty_acids ( 108 ) , G-1 ( 1 ) , G-CSF ( 449 ) , GAB-001 ( 120 ) , GAB-004 ( 120 ) , GDNF ( 396 ) , gefitinib ( 132 , 452 ) , genistein ( 411 , 490 , 572 , 579 ) , geranylgeranyl pyrophosphate ( 74 ) , GF109203X ( 474 , 521 ) , GGTI-298 ( 74 ) , glucosamine ( 398 ) , glucose ( 18 , 307 , 319 , 332 , 334 , 340 , 387 , 398 , 438 ) , glucose_starvation ( 440 ) , glycine ( 260 ) , GM-CSF ( 367 , 416 ) , Go_6976 ( 274 , 326 , 393 , 474 ) , growth factor stimulation ( 117 ) , GSK2334470 ( 157 , 217 ) , guanosine ( 441 ) , GYY4137 ( 101 ) , H-89 ( 332 , 431 ) , H-CHO ( 285 ) , H2O2 ( 278 , 332 , 385 , 483 , 490 , 563 ) , haloperidol ( 523 ) , HC-5404 ( 14 ) , heating ( 133 ) , herstatin ( 553 ) , HGF ( 474 ) , high-fat diet ( 12 , 28 , 42 , 92 , 98 , 114 , 142 , 150 , 182 , 184 , 239 , 376 , 394 , 447 , 507 ) , high_cell_density ( 25 ) , high_glucose ( 18 , 29 , 63 , 85 , 87 , 313 ) , honokiol ( 296 ) , HU-210 ( 303 ) , HY-10249A ( 89 ) , hypercapnia ( 170 ) , hypertension ( 487 ) , hypoxia ( 100 , 150 ) , hypoxia/reoxygenation ( 307 ) , IBMX ( 178 , 270 , 332 , 492 ) , ibrutinib ( 118 , 120 ) , IC87114 ( 318 ) , ICAM-1 ( 461 ) , icatibant ( 450 , 487 ) , IDRX-42 ( 39 ) , ifenprodil ( 181 ) , IFN-gamma ( 76 , 121 , 441 , 534 , 567 ) , IgE ( 504 , 579 ) , IGF-1 ( 30 , 230 , 337 , 391 , 393 , 436 , 454 , 466 , 474 , 475 , 476 , 506 , 517 , 524 , 542 , 546 , 564 , 566 , 572 , 577 , 582 ) , IGF-2 ( 80 , 474 , 476 , 546 ) , IGFBP-4 ( 546 ) , IL-10 ( 509 ) , IL-13 ( 118 ) , IL-15 ( 78 ) , IL-1b ( 304 ) , IL-2 ( 19 , 435 , 557 ) , IL-21 ( 429 ) , IL-3 ( 94 , 339 , 383 , 429 , 489 , 569 ) , IL-4 ( 37 , 76 , 118 , 527 ) , IL-6 ( 300 , 543 ) , IL-7 ( 49 , 78 , 102 , 179 , 234 , 435 ) , imatinib ( 339 , 552 ) , inflammation ( 395 ) , INK-128 ( 35 ) , insulin ( 4 , 10 , 12 , 13 , 18 , 26 , 36 , 42 , 43 , 50 , 57 , 70 , 72 , 74 , 88 , 98 , 112 , 114 , 116 , 119 , 128 , 134 , 135 , 136 , 137 , 141 , 142 , 145 , 146 , 150 , 151 , 153 , 154 , 155 , 164 , 176 , 178 , 182 , 193 , 204 , 208 , 217 , 221 , 228 , 229 , 231 , 232 , 233 , 235 , 240 , 245 , 252 , 253 , 254 , 255 , 257 , 270 , 274 , 278 , 285 , 287 , 288 , 295 , 296 , 303 , 304 , 312 , 315 , 316 , 319 , 322 , 323 , 334 , 336 , 338 , 346 , 347 , 349 , 351 , 355 , 359 , 363 , 364 , 366 , 369 , 372 , 374 , 375 , 377 , 378 , 379 , 383 , 387 , 391 , 394 , 399 , 400 , 402 , 407 , 413 , 414 , 426 , 432 , 439 , 447 , 448 , 453 , 455 , 459 , 464 , 467 , 470 , 476 , 477 , 485 , 494 , 496 , 498 , 501 , 502 , 507 , 508 , 510 , 513 , 528 , 535 , 541 , 556 , 560 , 564 , 565 , 568 , 571 , 576 , 577 ) , ionizing_radiation ( 247 , 391 ) , ionomycin ( 582 ) , ischemia ( 129 , 361 , 562 ) , ischemia/reperfusion ( 408 , 544 , 562 ) , isoflurane ( 184 ) , isoproterenol ( 151 , 178 , 250 ) , JAK_inhibitor_I ( 251 ) , Jatrorrhizine ( 63 ) , JNK_inhibitor_I ( 453 ) , ketamine ( 138 ) , KGF ( 474 ) , KirA6 ( 151 ) , KP-392 ( 559 ) , KU-0063794 ( 128 , 207 , 274 ) , L-lactate ( 92 ) , L-mevalonate ( 134 ) , L-NMMA ( 12 ) , laminar flow ( 520 ) , lapatinib ( 72 ) , latrunculin_A ( 206 ) , let-7 miRNA ( 288 ) , leucine ( 264 ) , levamfetamine ( 484 ) , LG268 ( 513 ) , LIF ( 505 ) , LIF withdrawal ( 209 ) , linagliptin ( 159 ) , linsitinib ( 30 ) , lithium ( 459 ) , long-term_potentiation ( 350 ) , low-fat diet ( 150 ) , low_glucose ( 122 ) , low_temperature ( 139 , 144 ) , LPA ( 115 ) , LPS ( 76 , 97 , 101 , 121 , 151 , 199 , 320 , 365 , 509 , 532 , 534 , 549 , 558 , 559 ) , Lugol ( 6 ) , LY294002 ( 23 , 68 , 87 , 103 , 121 , 138 , 148 , 171 , 182 , 208 , 216 , 217 , 251 , 255 , 256 , 273 , 274 , 289 , 316 , 320 , 354 , 356 , 365 , 383 , 388 , 396 , 403 , 411 , 414 , 447 , 448 , 458 , 463 , 466 , 484 , 490 , 503 , 505 , 506 , 509 , 512 , 514 , 515 , 520 , 521 , 524 , 525 , 530 , 534 , 547 , 552 , 557 , 562 , 569 , 574 , 577 , 579 ) , M-CSF ( 427 , 442 , 548 ) , magnetic_field,_coherent ( 180 ) , meal feeding ( 295 , 313 ) , mechanical stress ( 243 , 274 ) , memantine ( 473 ) , metamfetamine ( 181 ) , metformin ( 259 , 408 ) , methotrexate ( 537 ) , methyl-beta-cyclodextrin ( 294 ) , MG132 ( 271 ) , miR-143 ( 312 ) , miRNA ( 66 , 153 , 211 ) , MK-2206 ( 2 , 29 , 81 , 84 , 85 , 170 , 217 , 244 , 255 ) , MK801 ( 524 ) , MMS ( 462 ) , Mn(2+) ( 30 ) , MPTP ( 471 ) , MRS-1523 ( 420 ) , mutation ( 273 ) , myocardial infarction ( 231 ) , myostatin ( 436 ) , N-cadherin ( 344 ) , NAC ( 83 , 278 , 563 ) , NBD_peptide ( 264 ) , nerve_damage ( 271 ) , neuregulin ( 156 ) , NGF ( 292 ) , Ni(2+) ( 324 ) , nicardipine ( 487 ) , nitric_oxide ( 515 ) , NKH_477 ( 10 , 270 ) , NP68 ( 356 ) , NT157 ( 18 ) , nutlin-3 ( 216 ) , NVP-AEW541 ( 30 ) , NVP-BKM120 ( 67 , 157 , 193 , 244 ) , obesity-inducing diet ( 63 ) , OGD/R ( 129 ) , okadaic_acid ( 43 , 315 , 414 , 452 , 474 , 484 , 488 , 566 ) , OVA ( 242 ) , ovariectomy ( 1 ) , PA ( 375 ) , PAG ( 61 ) , palmitate ( 26 , 88 , 154 , 182 , 287 , 336 , 407 , 422 , 453 ) , PAN ( 325 ) , PAR1-activating_peptide ( 95 , 521 ) , PAR4-activating_peptide ( 521 ) , PcActx peptide ( 99 ) , PD0325901 ( 132 ) , PD123319 ( 450 , 487 ) , PD98059 ( 208 ) , PDGF ( 55 , 115 , 128 , 351 , 381 , 428 , 430 , 431 , 454 , 455 , 538 , 574 , 575 , 577 ) , Pentadecanoic acid ( 155 ) , peptidoglycan ( 151 ) , perillyl alcohol ( 74 ) , PF 573228 ( 171 ) , PF-4708671 ( 273 ) , PGE2 ( 318 , 332 ) , PHA-665752 ( 171 ) , phentolamine ( 314 ) , phorbol_ester ( 269 , 474 , 521 , 582 ) , physostigmine ( 473 ) , PI-103 ( 409 ) , picropodophyllin ( 506 ) , pictilisib ( 157 ) , PIF ( 411 ) , PIK90 ( 378 ) , pilocarpine ( 473 ) , PIP3 ( 158 ) , pleiotrophin ( 415 ) , PLX3397 ( 16 ) , PLX4032 ( 75 ) , poly(I-C) ( 128 , 320 ) , poly-L-lysine ( 47 ) , PP1 ( 107 ) , PP2 ( 107 , 256 , 517 ) , PP242 ( 182 , 242 , 345 , 378 ) , pregnancy ( 437 ) , pressure ( 389 ) , PRLi ( 51 ) , propranolol ( 165 ) , protozoan infection ( 93 ) , PTX ( 318 ) , racepinefrine ( 10 ) , RAD001 ( 35 , 397 ) , Radix Rehmanniae Praeparata ( 53 ) , RANKL ( 23 , 491 ) , rapamycin ( 2 , 102 , 135 , 182 , 225 , 230 , 247 , 273 , 274 , 288 , 295 , 318 , 328 , 334 , 336 , 337 , 345 , 346 , 348 , 355 , 356 , 364 , 378 , 383 , 393 , 399 , 414 , 418 , 444 , 447 , 448 , 454 , 459 , 462 , 475 , 485 , 494 ) , refeeding ( 232 , 315 , 352 ) , resatorvid ( 97 ) , resveratrol ( 278 ) , RGD ( 493 ) , RGE ( 493 ) , rigosertib ( 125 ) , ritonavir ( 64 ) , RMC-6272 ( 35 ) , rosiglitazone ( 296 , 460 , 513 ) , rottlerin ( 474 ) , S961 ( 27 ) , SB202190 ( 445 ) , SB203580 ( 154 , 328 , 514 ) , SBI-0206965 ( 176 ) , SC-79 ( 37 ) , SCF ( 392 , 458 , 530 ) , serum ( 67 , 123 , 128 , 243 , 288 , 327 , 330 , 341 , 348 , 379 , 448 , 454 , 455 , 457 , 474 , 483 , 547 , 582 ) , serum_starvation ( 204 , 264 , 288 , 379 , 448 ) , serum_withdrawal ( 514 ) , Shh ( 403 ) , SHP099 ( 118 , 142 ) , simvastatin ( 74 , 134 ) , siRNA ( 37 , 56 , 67 , 77 , 120 , 301 , 374 , 399 , 410 , 426 , 453 , 457 , 467 , 502 ) , skin aging ( 196 ) , SN-50 ( 549 ) , SP600125 ( 477 , 517 ) , sphingomyelinase ( 202 , 313 ) , sphingosine_1-phosphate ( 87 , 223 ) , SPT ( 420 ) , SRT2104 ( 55 ) , starvation ( 67 ) , starvation_medium ( 264 ) , staurosporine ( 551 ) , streptozotocin ( 184 ) , SU5402 ( 463 ) , SU6656 ( 452 ) , sulforaphane ( 443 ) , sulprostone ( 318 ) , sVCAM-1 ( 461 ) , t-butanol ( 490 ) , tamoxifen ( 423 ) , TGF-alpha ( 553 ) , TGF-beta ( 211 , 532 , 543 , 578 ) , thapsigargin ( 151 , 289 ) , Theophylline ( 420 ) , thrombin ( 284 , 521 ) , TNF ( 124 , 151 , 304 , 441 , 462 , 467 , 477 , 549 , 566 , 581 ) , Toluidine blue O ( 65 ) , topotecan ( 247 ) , Torin1 ( 102 , 128 , 182 , 217 , 318 , 325 ) , TPCK ( 549 ) , trastuzumab ( 96 ) , triciribine ( 305 ) , troglitazone ( 465 , 475 ) , tucatinib ( 96 ) , TUG-891 ( 203 ) , tunicamycin ( 386 ) , U0126 ( 198 , 334 , 356 , 383 , 420 , 425 , 447 , 459 , 463 , 483 , 492 , 555 ) , UV ( 500 , 545 , 563 ) , UVB ( 196 ) , vanadate ( 267 , 332 ) , VAT-R ( 141 ) , VEGF ( 393 , 522 ) , vemurafenib ( 110 ) , versikine ( 169 ) , VIIa ( 323 ) , virus infection ( 170 ) , Visudyne ( 87 , 115 ) , vitronectin ( 493 ) , VPS34-IN1 ( 157 ) , Weigela florida ( 82 ) , WIN ( 525 ) , Wnt ( 459 , 546 ) , Wnt3a ( 459 ) , wortmannin ( 84 , 129 , 178 , 190 , 204 , 229 , 273 , 305 , 318 , 334 , 336 , 346 , 356 , 364 , 388 , 399 , 425 , 436 , 447 , 454 , 459 , 461 , 472 , 475 , 485 , 498 , 501 , 509 , 512 , 538 , 547 , 549 , 552 , 566 , 574 , 575 , 577 , 579 , 580 ) , XL-147 ( 189 ) , YM-254890 ( 203 )

acetylation ( 152 ) , activity, induced ( 243 , 250 ) , enzymatic activity, induced ( 2 , 17 , 72 , 81 , 82 , 99 , 105 , 147 , 148 , 234 , 265 , 268 , 278 , 282 , 283 , 319 , 371 , 385 , 398 , 514 , 521 , 524 , 540 , 552 , 553 , 579 ) , intracellular localization ( 17 , 18 , 99 , 152 , 278 , 560 , 572 ) , molecular association, regulation ( 277 , 315 ) , phosphorylation ( 2 , 81 , 126 , 148 , 152 , 265 , 274 , 315 , 322 ) , protein degradation ( 277 ) , ubiquitination ( 277 )

apoptosis, altered ( 268 , 333 , 385 ) , apoptosis, inhibited ( 17 , 55 , 61 , 100 , 105 , 120 , 121 , 129 , 244 , 265 , 370 ) , autophagy, inhibited ( 25 , 40 , 106 ) , carcinogenesis, altered ( 115 ) , carcinogenesis, induced ( 2 , 29 , 32 , 47 , 61 , 67 , 89 , 90 , 124 , 125 , 127 , 146 , 147 , 149 , 162 , 171 , 212 , 244 , 261 ) , carcinogenesis, inhibited ( 81 ) , cell cycle regulation ( 49 , 61 , 81 , 244 , 421 ) , cell differentiation, altered ( 93 ) , cell differentiation, induced ( 21 , 23 , 49 , 103 , 108 , 127 , 283 ) , cell growth, altered ( 370 , 561 ) , cell growth, induced ( 21 , 32 , 49 , 55 , 61 , 67 , 72 , 77 , 89 , 105 , 117 , 124 , 127 , 134 , 147 , 149 , 156 , 162 , 180 , 244 , 294 ) , cell growth, inhibited ( 81 , 115 ) , cell motility, induced ( 47 , 61 , 89 , 115 , 120 , 131 , 146 , 261 ) , cell motility, inhibited ( 64 ) , cytoskeletal reorganization ( 89 , 370 ) , neural plasticity ( 268 ) , RNA splicing, induced ( 192 ) , RNA stability, induced ( 103 ) , signaling pathway regulation ( 2 , 3 , 17 , 99 , 157 , 171 , 184 , 249 , 250 , 251 , 254 , 268 , 283 , 301 , 338 , 393 ) , transcription, altered ( 17 , 127 , 141 ) , transcription, induced ( 48 , 80 , 81 , 82 , 87 , 101 , 579 ) , transcription, inhibited ( 106 , 144 , 265 , 278 ) , translation, induced ( 2 , 27 , 73 , 111 ) , translation, inhibited ( 265 )

CHIP (human) ( 277 ) , PPP2CA (human) ( 315 ) , PPP2R5B (mouse) ( 315 )

Alzheimer's disease ( 53 , 79 ) , colorectal cancer ( 29 ) , endometrial cancer ( 469 ) , melanoma skin cancer ( 2 , 213 ) , cardiomyopathy ( 87 ) , colonic inflamation ( 52 ) , diabetes mellitus ( 29 , 83 , 85 , 87 , 164 ) , type 2 diabetes ( 447 , 460 , 516 ) , Huntington's disease ( 161 ) , Turner-like syndrome ( 142 )