Lys549

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Home > Ubiquitylation Site Page: > Lys549 - GLT1 (mouse)

Site Information
sVVIDECkVTLAAnG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 4667700

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	bone cancer ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , astrocyte ( 1 ) , brain ( 1 ) , U2OS (bone cell) ( 1 )

Downstream Regulation
Effects of modification on GLT1:	molecular association, regulation ( 1 )
Induce interaction with:	GLT1 (human) ( 1 )

References
1	Sha L, et al. (2022) Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice. JCI Insight 7 35938532 Curated Info

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