Ser30
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Home > Phosphorylation Site Page: > Ser30  -  claspin (human)

Site Information
EADSPSDsGQGsYET   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 467250

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PLK1 (human) ( 1 )
Treatments:
hydroxyurea ( 1 ) , UV ( 1 )

Downstream Regulation
Effects of modification on claspin:
molecular association, regulation ( 1 ) , protein degradation ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )
Induce interaction with:
BTRC (human) ( 1 )

References 

1

Peschiaroli A, et al. (2006) SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response. Mol Cell 23, 319-29
16885022   Curated Info