Ser177
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Home > Phosphorylation Site Page: > Ser177  -  IKKB (rat)

Site Information
AKELDQGsLCTsFVG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447492

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Regulatory protein:
IKKB (rat) ( 2 ) , PKCE (rat) ( 2 )
Treatments:
anisomycin ( 2 ) , insulin ( 2 ) , palmitate ( 2 ) , phorbol_ester ( 2 )

References 

1

Tang CH, et al. (2007) Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-kappaB, and p300 pathway in microglia. J Immunol 179, 1292-302
17617622   Curated Info

2

Herschkovitz A, et al. (2007) Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance. J Biol Chem 282, 18018-27
17446166   Curated Info