Ser347
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Home > Phosphorylation Site Page: > Ser347  -  Myc (human)

Site Information
RKCtsPrssDtEENV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 466010

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 2 )
Disease tissue studied:
neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CK2A1 (human) ( 2 )

Downstream Regulation
Effects of modification on biological processes:
carcinogenesis, inhibited ( 1 ) , transcription, inhibited ( 1 )

References 

1

Wasylishen AR, et al. (2013) MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity. Cancer Res 73, 6504-15
24030976   Curated Info

2

L├╝scher B, Kuenzel EA, Krebs EG, Eisenman RN (1989) Myc oncoproteins are phosphorylated by casein kinase II. EMBO J 8, 1111-9
2663470   Curated Info