Tyr309
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Home > Phosphorylation Site Page: > Tyr309  -  FCGR2B (mouse)

Site Information
EAENTITySLLkHPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448507
Associated spectra:  2 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 ) , mutation of modification site ( 4 ) , phospho-antibody ( 4 ) , western blotting ( 4 )
Disease tissue studied:
lymphoma ( 4 ) , B cell lymphoma ( 4 )
Relevant cell line - cell type - tissue:
A20 (B lymphocyte) ( 4 ) , liver ( 1 , 2 , 3 ) , liver [leptin (mouse), homozygous knockout] ( 1 )

Upstream Regulation
Treatments:
anti-FcRII ( 4 )

Downstream Regulation
Effects of modification on FCGR2B:
activity, induced ( 4 ) , phosphorylation ( 4 )

References 

1

Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83
23140645   Curated Info

2

Guo A (2007) CST Curation Set: 2986; Year: 2007; Biosample/Treatment: tissue, liver/Insulin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Villén J, Beausoleil SA, Gerber SA, Gygi SP (2007) Large-scale phosphorylation analysis of mouse liver. Proc Natl Acad Sci U S A 104, 1488-93
17242355   Curated Info

4

Fong DC, et al. (2000) Mutational analysis reveals multiple distinct sites within Fc gamma receptor IIB that function in inhibitory signaling. J Immunol 165, 4453-62
11035084   Curated Info