Ser207
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Home > Acetylation Site Page: > Ser207  -  MKK6 (human)

Site Information
IsGyLVDsVAKtIDA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4325701

In vivo Characterization
Methods used to characterize site in vivo:
phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
Flp-In T-Rex-293 (epithelial) ( 1 )

Upstream Regulation
Regulatory protein:
APOL1 (human) ( 1 )

Downstream Regulation
Effects of modification on MKK6:
enzymatic activity, inhibited ( 2 ) , phosphorylation ( 2 )

References 

1

Olabisi OA, et al. (2016) APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases. Proc Natl Acad Sci U S A 113, 830-7
26699492   Curated Info

2

Mukherjee S, et al. (2006) Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science 312, 1211-4
16728640   Curated Info

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