Tyr15
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Home > Phosphorylation Site Page: > Tyr15  -  CDK1 (chicken)

Site Information
EKIGEGtyGVVYKGR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447610

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , phospho-antibody ( 1 ) , phosphoamino acid analysis ( 2 ) , phosphopeptide mapping ( 2 ) , western blotting ( 1 )
Disease tissue studied:
liver cancer ( 2 ) , lymphoma ( 1 ) , B cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:
DT40 (B lymphocyte) ( 1 ) , DU429 (hepatic) ( 2 )

Upstream Regulation
Kinases, in vitro:
Src (human) ( 2 )
Treatments:
ionizing_radiation ( 1 )

References 

1

Xu N, et al. (2012) Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage. Oncogene 31, 1086-94
21765472   Curated Info

2

Krek W, Nigg EA (1991) Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites. EMBO J 10, 305-16
1846803   Curated Info