Ser208
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Home > Phosphorylation Site Page: > Ser208  -  p47phox (mouse)

Site Information
KRGWVPAsYLEPLDS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 465580

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
COS7 (fibroblast) ( 1 ) , HEK293T (epithelial) ( 1 ) , lung ( 1 ) , neutrophil ( 1 )

Upstream Regulation
Putative in vivo kinases:
MEKK2 (human) ( 1 ) , MEKK3 (human) ( 1 )
Kinases, in vitro:
MEKK2 (human) ( 1 ) , MEKK3 (mouse) ( 1 )
Treatments:
fMLP ( 1 ) , pazopanib ( 1 )

Downstream Regulation
Effects of modification on p47phox:
molecular association, regulation ( 1 ) , phosphorylation ( 1 )
Inhibit interaction with:
CYBA (mouse) ( 1 )

References 

1

Yuan Q, et al. (2021) Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3. Sci Transl Med 13
33910977   Curated Info