Ser276
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Home > Phosphorylation Site Page: > Ser276  -  AQP4 (human)

Site Information
AAQQTKGsyMEVEDN   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 465556

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lung cancer ( 2 ) , non-small cell lung adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , lung ( 2 )

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )

Downstream Regulation
Effects of modification on AQP4:
intracellular localization ( 1 )

References 

1

Kitchen P, et al. (2015) Identification and Molecular Mechanisms of the Rapid Tonicity-induced Relocalization of the Aquaporin 4 Channel. J Biol Chem 290, 16873-81
26013827   Curated Info

2

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info