Ser766
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Home > Phosphorylation Site Page: > Ser766  -  TNIK (human)

Site Information
RVRANsKsEGsPVLP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4269871

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 , 5 , 6 , 7 , 8 )
Disease tissue studied:
lung cancer ( 3 , 4 ) , non-small cell lung cancer ( 4 ) , non-small cell lung adenocarcinoma ( 3 ) , melanoma skin cancer ( 2 )
Relevant cell line - cell type - tissue:
'brain, cerebral cortex' ( 5 ) , 293 (epithelial) ( 7 ) , HeLa_Meta (cervical) ( 6 ) , HeLa_Pro (cervical) ( 6 ) , HeLa_Telo (cervical) ( 6 ) , HOP62 (pulmonary) ( 4 ) , lung ( 3 ) , MDA-MB-435S (breast cell) ( 8 ) , MV4-11 (macrophage) ( 8 ) , NCI-H1568 (pulmonary) ( 4 ) , NCI-H157 (pulmonary) ( 4 ) , NCI-H1666 (pulmonary) ( 4 ) , NCI-H322 (pulmonary) ( 4 ) , NCI-H520 (squamous) ( 4 ) , NCI-H647 (pulmonary) ( 4 ) , PC9 (pulmonary) ( 4 ) , WM239A (melanocyte) ( 2 )

References 

1

Boeing S, et al. (2016) Multiomic Analysis of the UV-Induced DNA Damage Response. Cell Rep 15, 1597-1610
27184836   Curated Info

2

Stuart SA, et al. (2015) A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells. Mol Cell Proteomics 14, 1599-615
25850435   Curated Info

3

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info

4

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

5

Herskowitz JH, et al. (2010) Phosphoproteomic Analysis Reveals Site-Specific Changes in GFAP and NDRG2 Phosphorylation in Frontotemporal Lobar Degeneration. J Proteome Res 9, 6368-79
20886841   Curated Info

6

Dulla K, et al. (2010) Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9, 1167-81
20097925   Curated Info

7

Guo A (2010) CST Curation Set: 6270; Year: 2010; Biosample/Treatment: cell line, 293/rapamycin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST]
Curated Info

8

Oppermann FS, et al. (2009) Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics 8, 1751-64
19369195   Curated Info