Thr150
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Home > Phosphorylation Site Page: > Thr150  -  SIRT3 (human)

Site Information
MVGAGIStPSGIPDF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 41655507

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
brain cancer ( 1 ) , glioblastoma ( 1 ) , glioma ( 1 ) , breast cancer ( 1 ) , colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
CDK1 (human) ( 1 )
Kinases, in vitro:
CDK1 (human) ( 1 )
Treatments:
ionizing_radiation ( 1 )

Downstream Regulation
Effects of modification on SIRT3:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Liu R, et al. (2015) CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther 14, 2090-102
26141949   Curated Info