Tyr191

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Home > Phosphorylation Site Page: > Tyr191 - NPM-ALK (human)

Site Information
HGAFGEVyEGQVSGM GenPept
Blast this site against: NCBI SwissProt PDB
Site Group ID: 27275114
Associated spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 )
Relevant cell line - cell type - tissue:	293GP (epithelial) ( 1 , 2 )

References
1	Wang P, et al. (2011) Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential. Carcinogenesis 32, 146-53 21045017 Curated Info
2	Wang P, et al. (2010) Functional characterization of the kinase activation loop in nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) using tandem affinity purification and liquid chromatography-mass spectrometry. J Biol Chem 285, 95-103 19887368 Curated Info

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