Ser1027
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Home > Phosphorylation Site Page: > Ser1027  -  ULK2 (human)

Site Information
CSIERRLsALCHSTA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 41294001

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKACA (human) ( 1 )

Downstream Regulation
Effects of modification on ULK2:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
autophagy, inhibited ( 1 )
Inhibit interaction with:
ATG101 (human) ( 1 ) , RB1CC1 (human) ( 1 )

References 

1

Shin SH, et al. (2015) ULK2 Ser 1027 Phosphorylation by PKA Regulates Its Nuclear Localization Occurring through Karyopherin Beta 2 Recognition of a PY-NLS Motif. PLoS One 10, e0127784
26052940   Curated Info