Thr1396

Site Information
FSNskAYtPskRSRI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 41287146

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	breast cancer ( 2 ) , breast ductal carcinoma ( 2 ) , breast cancer, surrounding tissue ( 1 ) , breast cancer, triple negative ( 2 )
Relevant cell line - cell type - tissue:	breast ( 1 , 2 ) , HeLa S3 (cervical) [PLK1 (human), knockdown, Tet-inducible PLK1 siRNA] ( 3 ) , HeLa S3 (cervical) ( 3 )

References
1	Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62 27251275 Curated Info
2	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
3	Santamaria A, et al. (2011) The Plk1-dependent phosphoproteome of the early mitotic spindle. Mol Cell Proteomics 10, M110.004457 20860994 Curated Info