Ser345
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Home > Phosphorylation Site Page: > Ser345  -  TTK (human)

Site Information
PLVSDEKsSELIItD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 41157083

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 )
Relevant cell line - cell type - tissue:
HeLa_Meta (cervical) ( 2 ) , HeLa_Pro (cervical) ( 2 ) , HeLa_Telo (cervical) ( 2 )

Upstream Regulation
Kinases, in vitro:
PLK1 (human) ( 1 )
Treatments:
MG132_withdrawal ( 2 )

Downstream Regulation
Effects of modification on TTK:
enzymatic activity, induced ( 1 ) , intracellular localization ( 1 )

References 

1

von Schubert C, et al. (2015) Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells. Cell Rep 12, 66-78
26119734   Curated Info

2

Dulla K, et al. (2010) Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9, 1167-81
20097925   Curated Info