Ser484
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Home > Phosphorylation Site Page: > Ser484  -  Kv7.1 (human)

Site Information
PHFMRtNsFAEDLDL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 40556220

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
cardiomyopathy ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
CAMK2D (human) ( 1 )
Kinases, in vitro:
CAMK2D (human) ( 1 )
Treatments:
isoproterenol ( 1 )

Downstream Regulation
Effects of modification on Kv7.1:
activity, inhibited ( 1 )

References 

1

Shugg T, et al. (2018) Calcium/calmodulin-dependent protein kinase II regulation of Iduring sustained β-adrenergic receptor stimulation. Heart Rhythm
29410121   Curated Info

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