Ser309
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Home > Phosphorylation Site Page: > Ser309  -  USF1 (mouse)

Site Information
EVVIKNDsN______   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 40515061

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 3 ) , endothelial ( 1 ) , HEK293T (epithelial) ( 1 ) , stromal ( 2 )

Upstream Regulation
Putative upstream phosphatases:
PTP4A1 (human) ( 1 )
Treatments:
insulin ( 3 ) , MK-2206 ( 3 )

Downstream Regulation
Effects of modification on USF1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
DNA ( 1 )

References 

1

Cho MJ, et al. (2022) Endothelial PTP4A1 mitigates vascular inflammation via USF1/A20 axis-mediated NF-κB inactivation. Cardiovasc Res
36534975   Curated Info

2

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

3

Humphrey SJ, et al. (2013) Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2. Cell Metab 17, 1009-20
23684622   Curated Info

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