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Site Information |
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GRVTLFPkDVQLARR SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 40439801 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: |
Downstream Regulation | |
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Effects of modification on CENPA: | |
Effects of modification on biological processes: | |
Induce interaction with: |
References | |
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Wang K, et al. (2021) Phosphorylation at Ser68 facilitates DCAF11-mediated ubiquitination and degradation of CENP-A during the cell cycle. Cell Rep 37, 109987
34758320 Curated Info |
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Salinas-Luypaert C, et al. (2021) Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-A. Cell Rep 37, 109924
34731637 Curated Info |
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Niikura Y, Kitagawa R, Fang L, Kitagawa K (2019) CENP-A Ubiquitylation Is Indispensable to Cell Viability. Dev Cell 50, 683-689.e6
31550462 Curated Info |
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Fachinetti D, et al. (2017) CENP-A Modifications on Ser68 and Lys124 Are Dispensable for Establishment, Maintenance, and Long-Term Function of Human Centromeres. Dev Cell 40, 104-113
28073008 Curated Info |
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Niikura Y, et al. (2015) CENP-A K124Â Ubiquitylation Is Required for CENP-A Deposition at the Centromere. Dev Cell 32, 589-603
25727006 Curated Info |