Thr659
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Home > Phosphorylation Site Page: > Thr659  -  DLK (mouse)

Site Information
GARGRGAtGGARDPG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 40416400

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
ES (stem) ( 1 )

Upstream Regulation
Kinases, in vitro:
Akt1 (mouse) ( 1 )

Downstream Regulation
Effects of modification on DLK:
enzymatic activity, inhibited ( 1 )
Effects of modification on biological processes:
cell growth, induced ( 1 )

References 

1

Wu CC, et al. (2015) Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells. Cell Cycle 14, 1207-17
25802931   Curated Info