Ser1934
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Home > Phosphorylation Site Page: > Ser1934  -  SCN5A (human)

Site Information
LFRQQAGsGLsEEDA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 40413914

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mass spectrometry (in vitro) ( 2 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 )

Upstream Regulation
Kinases, in vitro:
CAMK2A (human) ( 2 )

Downstream Regulation
Effects of modification on SCN5A:
activity, induced ( 1 ) , molecular association, regulation ( 1 )
Inhibit interaction with:
Calmodulin (mouse) ( 1 ) , FGF13 (mouse) ( 1 )

References 

1

Burel S, et al. (2017) C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation. J Biol Chem 292, 17431-17448
28882890   Curated Info

2

Herren AW, et al. (2015) CaMKII Phosphorylation of Na(V)1.5: Novel in Vitro Sites Identified by Mass Spectrometry and Reduced S516 Phosphorylation in Human Heart Failure. J Proteome Res 14, 2298-311
25815641   Curated Info

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