Lys1136

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Home > Ubiquitylation Site Page: > Lys1136 - WNK4 (mouse)

Site Information
EALQTLQkkEIEDLY SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 40323314

In vivo Characterization
Methods used to characterize site in vivo:	immunoassay ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	COS7 (fibroblast) ( 1 ) , kidney ( 1 )

Upstream Regulation
Regulatory protein:	KLHL3 (mouse) ( 1 )

Downstream Regulation
Effects of modification on WNK4:	protein degradation ( 1 )

References
1	Shibata S, et al. (2013) Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4. Proc Natl Acad Sci U S A 110, 7838-43 23576762 Curated Info

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