Tyr381
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.8.0
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr381  -  cytohesin 2 (mouse)

Site Information
AVSVDPFyEMLAARK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 4003314

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , RT-4 Schwannoma (Schwann) ( 1 ) , sciatic nerve ( 1 )

Upstream Regulation
Regulatory protein:
PTP1B (human) ( 1 ) , PTPN13 (human) ( 1 ) , PTPN2 (human) ( 1 ) , SH2-B-beta (human) ( 1 )
Putative in vivo kinases:
Fyn (mouse) ( 1 )
Putative upstream phosphatases:
PTP4A1 (mouse) ( 1 )
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on cytohesin 2:
activity, induced ( 1 ) , molecular association, regulation ( 1 )
Induce interaction with:
ARF6 (human) ( 1 ) , GGA3 (human) ( 1 ) , SH2-B-beta (human) ( 1 )

References 

1

Miyamoto Y, et al. (2022) The adaptor SH2B1 and the phosphatase PTP4A1 regulate the phosphorylation of cytohesin-2 in myelinating Schwann cells in mice. Sci Signal 15, eabi5276
35077201   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.