Tyr181
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Home > Phosphorylation Site Page: > Tyr181  -  RKIP (mouse)

Site Information
DDYVPKLyEQLsGk_   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 464183

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 )
Disease tissue studied:
testicular cancer ( 4 )
Relevant cell line - cell type - tissue:
P19 (testicular) ( 4 ) , PYS-2 (epithelial) ( 5 ) , RAW 264.7 (macrophage) ( 1 ) , spermatozoa ( 2 ) , spermatozoa [CATSPER1 (mouse), homozygous knockout] ( 2 ) , SYF (fibroblast) [Src iso1 (mouse), transfection] ( 3 )

Upstream Regulation
Regulatory protein:
CATSPER1 (mouse) ( 2 )

References 

1

Pinto SM, et al. (2015) Quantitative phosphoproteomic analysis of IL-33-mediated signaling. Proteomics 15, 532-44
25367039   Curated Info

2

Chung JJ, et al. (2014) Structurally distinct Ca(2+) signaling domains of sperm flagella orchestrate tyrosine phosphorylation and motility. Cell 157, 808-22
24813608   Curated Info

3

Ferrando IM, et al. (2012) Identification of targets of c-Src tyrosine kinase by chemical complementation and phosphoproteomics. Mol Cell Proteomics 11, 355-69
22499769   Curated Info

4

Zhou J (2010) CST Curation Set: 9109; Year: 2010; Biosample/Treatment: cell line, P19/untreated; Disease: testicular cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info

5

Zhou J (2010) CST Curation Set: 9108; Year: 2010; Biosample/Treatment: cell line, PY2/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-102) Cat#: 9416
Curated Info