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Powered by Cell Signaling Technology |
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Powered by Cell Signaling Technology |
| Site Information |
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| sSYGGLTsPGFSYGM SwissProt Entrez-Gene |
| Blast this site against: NCBI SwissProt PDB |
| Site Group ID: 448540 |
| In vivo Characterization | |
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| Methods used to characterize site in vivo: | |
| Relevant cell line - cell type - tissue: | |
| Upstream Regulation | |
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| Putative in vivo kinases: | |
| Treatments: | |
| Downstream Regulation | |
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| Effects of modification on K8: | |
| Effects of modification on biological processes: | |
| References | |
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Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83
23140645 Curated Info |
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Fortier AM, Riopel K, Désaulniers M, Cadrin M (2010) Novel insights into changes in biochemical properties of keratins 8 and 18 in griseofulvin-induced toxic liver injury. Exp Mol Pathol 89, 117-25
20643122 Curated Info |
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Guo A (2009) CST Curation Set: 7790; Year: 2009; Biosample/Treatment: tissue, liver/Metformin; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) PKD Substrate Antibody Cat#: 4381, PTMScan(R) Phospho-PKD Substrate Motif (LXRXXpS/pT) Immunoaffinity Beads Cat#: 1986
Curated Info |
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Zhou J (2009) CST Curation Set: 7435; Year: 2009; Biosample/Treatment: tissue, liver/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pSP
Curated Info |
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Zhou J (2009) CST Curation Set: 7434; Year: 2009; Biosample/Treatment: tissue, liver/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pSP
Curated Info |
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Rikova K (2008) CST Curation Set: 4508; Year: 2008; Biosample/Treatment: cell line, MD Ander 1154/untreated; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: RXXp[ST] Antibodies Used to Purify Peptides prior to LCMS: Phospho-Akt Substrate (RXRXXS/T) (110B7) Rabbit mAb Cat#: 9614, PTMScan(R) Phospho-Akt Substrate Motif (RXXS*/T*) Immunoaffinity Beads Cat#: 1978
Curated Info |
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Nan L, et al. (2006) Mallory body (cytokeratin aggresomes) formation is prevented in vitro by p38 inhibitor. Exp Mol Pathol 80, 228-40
16563375 Curated Info |
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Fausther M, Villeneuve L, Cadrin M (2004) Heat shock protein 70 expression, keratin phosphorylation and Mallory body formation in hepatocytes from griseofulvin-intoxicated mice. Comp Hepatol 3, 5
15307891 Curated Info |
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Stumptner C, et al. (2000) Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a mallory body mouse model. Am J Pathol 156, 77-90
10623656 Curated Info |
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