Thr768
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Home > Phosphorylation Site Page: > Thr768  -  Diaphanous-1 (human)

Site Information
PVLPFGLtPKkLykP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3946102

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry (in vitro) ( 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CDK1 (human) ( 2 )
Treatments:
cAMP_analog ( 1 )

Downstream Regulation
Effects of modification on Diaphanous-1:
molecular association, regulation ( 1 ) , protein degradation ( 1 )
Induce interaction with:
ACTB (human) ( 1 ) , KIF1A (human) ( 1 )

References 

1

Li D, Dammer EB, Lucki NC, Sewer MB (2013) cAMP-stimulated phosphorylation of diaphanous 1 regulates protein stability and interaction with binding partners in adrenocortical cells. Mol Biol Cell 24, 848-57
23325789   Curated Info

2

Blethrow JD, Glavy JS, Morgan DO, Shokat KM (2008) Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates. Proc Natl Acad Sci U S A 105, 1442-7
18234856   Curated Info