Thr2122
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Home > Phosphorylation Site Page: > Thr2122  -  Notch 1 (mouse)

Site Information
HGTALGGtPTLSPTL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 386186602

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Phosphatases, in vitro:
EYA1 (mouse) ( 1 )

Downstream Regulation
Effects of modification on Notch 1:
protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
cell differentiation, inhibited ( 1 )

References 

1

Zhang H, et al. (2017) An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis. Elife 6
29140246   Curated Info