Lys178
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Home > Ubiquitylation Site Page: > Lys178  -  TGFBR1 (human)

Site Information
IsEGTtLkDLIyDMt   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 38557705

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
prostate cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
TGF-beta ( 1 )

Downstream Regulation
Effects of modification on TGFBR1:
intracellular localization ( 1 )
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , cell cycle regulation ( 1 ) , transcription, induced ( 1 )

References 

1

Sundar R, Gudey SK, Heldin CH, Landström M (2015) TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor. Cell Cycle 14, 554-65
25622187   Curated Info