Lys121
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.4
Powered by Cell Signaling Technology
Home > Acetylation Site Page: > Lys121  -  C/EBP-epsilon (human)

Site Information
DPRAVAVkEEPRGPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 38557701

In vivo Characterization
Methods used to characterize site in vivo:
immunoassay ( 1 ) , immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 1 ) , acute myelogenous leukemia ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 ) , HL60 (myeloid) ( 1 ) , NB-4 (myeloid) ( 1 ) , neutrophil ( 1 )

Upstream Regulation
Treatments:
nicotinamide ( 1 ) , valproic acid ( 1 )

Downstream Regulation
Effects of modification on C/EBP-epsilon:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell differentiation, induced ( 1 ) , transcription, induced ( 1 )
Induce interaction with:
DNA ( 1 )

References 

1

Bartels M, et al. (2015) Acetylation of C/EBPε is a prerequisite for terminal neutrophil differentiation. Blood 125, 1782-92
25568349   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2019 Cell Signaling Technology, Inc.