Ser84
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Home > Phosphorylation Site Page: > Ser84  -  Bcl-2 (mouse)

Site Information
ATAGPALsPVPPVVH   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448396

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 )
Relevant cell line - cell type - tissue:
NCI-H157 (pulmonary) ( 2 ) , NSF/N1.H7 (myeloid) ( 2 )

Downstream Regulation
Effects of modification on Bcl-2:
protein conformation ( 2 ) , protein stabilization ( 2 )
Effects of modification on biological processes:
apoptosis, inhibited ( 2 ) , cell cycle regulation ( 2 )

References 

1

Liu Y, et al. (2020) TLR9 and beclin┬┐┬┐1 crosstalk regulates muscle AMPK activation in exercise. Nature
32051584   Curated Info

2

Deng X, Gao F, Flagg T, May WS (2004) Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions. Proc Natl Acad Sci U S A 101, 153-8
14660795   Curated Info