Ser224
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Home > Phosphorylation Site Page: > Ser224  -  DUSP10 (human)

Site Information
SCREGKDsFKRIFsK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 38520204

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
brain cancer ( 1 ) , glioblastoma ( 1 ) , glioma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
mTOR (human) ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, induced ( 1 ) , cell growth, inhibited ( 1 )

References 

1

Benavides-Serrato A, et al. (2014) mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma. Genes Cancer 5, 393-406
25568665   Curated Info