Ser196

Site Information
QkSkEyFskQK____ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 38484864
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 )
Disease tissue studied:	breast cancer ( 1 ) , breast cancer, triple negative ( 1 ) , lung cancer ( 2 , 3 , 4 , 5 ) , non-small cell lung cancer ( 2 , 3 , 4 , 5 , 6 ) , non-small cell lung adenocarcinoma ( 2 , 3 , 4 , 5 , 6 ) , non-small cell large cell lung carcinoma ( 3 )
Relevant cell line - cell type - tissue:	A549 (pulmonary) ( 2 ) , breast ( 1 ) , Cal-12T (pulmonary) ( 5 ) , DMS153 (pulmonary) ( 4 ) , HCC44 (pulmonary) ( 5 ) , lung ( 2 , 3 , 4 , 5 ) , NCI-H1299 (pulmonary) ( 3 ) , NCI-H1355 (pulmonary) ( 2 ) , NCI-H1437 (pulmonary) ( 4 , 5 ) , NCI-H1666 (pulmonary) ( 5 ) , NCI-H1734 (pulmonary) ( 3 ) , NCI-H1792 (pulmonary) ( 2 ) , NCI-H1944 (pulmonary) ( 3 ) , NCI-H2073 (pulmonary) ( 4 ) , NCI-H209 (pulmonary) ( 4 ) , NCI-H2228 (pulmonary) ( 6 ) , NCI-H23 (pulmonary) ( 2 ) , NCI-H2405 (pulmonary) ( 5 ) , NCI-H358 (pulmonary) ( 3 ) , NCI-H441 (pulmonary) ( 2 ) , NCI-H460 (pulmonary) ( 3 ) , NCI-H838 (pulmonary) ( 4 )

References
1	Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704 24719451 Curated Info
2	Rikova K, Hall B (2013) CST Curation Set: 20736, 21163, 30158, 30159, 30160; Year: 2013; Biosample/Treatment: cell line, A549, H1355, H23, H441, H1792; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
3	Rikova K, Hall B (2013) CST Curation Set: 20737, 21164, 30161, 30162, 30163; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
4	Rikova K, Hall B (2013) CST Curation Set: 20742, 21169, 30176, 30177, 30178; Year: 2013; Biosample/Treatment: cell line, H838, DMS153, H2073, H209, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
5	Rikova K, Hall B (2013) CST Curation Set: 20741, 21168, 30173, 30174, 30175; Year: 2013; Biosample/Treatment: cell line, H1666, CAL-12T, H2405, HCC44, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
6	Rikova K (2013) CST Curation Set: 18449; Year: 2012; Biosample/Treatment: cell line, H2228/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954 Curated Info