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Home > Phosphorylation Site Page: > Thr344  -  TRF1 (human)

Site Information
KKERRVGtPQsTKKK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3793900

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 1 ) , mutation of modification site ( 1 , 3 ) , western blotting ( 3 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CDK1 (human) ( 3 )

Downstream Regulation
Effects of modification on TRF1:
phosphorylation ( 3 )



Sánchez-Vázquez R, Martínez P, Blasco MA (2021) AKT-dependent signaling of extracellular cues through telomeres impact on tumorigenesis. PLoS Genet 17, e1009410
33690611   Curated Info


Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info


Wu ZQ, Yang X, Weber G, Liu X (2008) Plk1 phosphorylation of TRF1 is essential for its binding to telomeres. J Biol Chem 283, 25503-13
18625707   Curated Info