Ser62
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Home > Phosphorylation Site Page: > Ser62  -  Chk2 (human)

Site Information
SSSGTLSsLETVSTQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3793200

In vivo Characterization
Methods used to characterize site in vivo:
flow cytometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
fibrosarcoma of soft tissue ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PLK3 (human) ( 1 )

References 

1

Bahassi el M, et al. (2006) Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage. Mutat Res 596, 166-76
16481012   Curated Info