Tyr18
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Home > Phosphorylation Site Page: > Tyr18  -  ZDHHC3 (mouse)

Site Information
DIERKPEyLQPEKCA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 462842
Associated spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 2 , 3 ) , chronic myelogenous leukemia ( 2 , 3 ) , neuroblastoma ( 1 )
Relevant cell line - cell type - tissue:
BaF3 ('B lymphocyte, precursor') ( 2 , 3 ) , Neuro-2a (neuron) ( 1 ) , SYF (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
FGFR1 (human) ( 1 )

Downstream Regulation
Effects of modification on ZDHHC3:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )

References 

1

Lievens PM, et al. (2016) ZDHHC3 Tyrosine Phosphorylation Regulates Neural Cell Adhesion Molecule Palmitoylation. Mol Cell Biol 36, 2208-25
27247265   Curated Info

2

Gu T (2007) CST Curation Set: 3408; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3 (D835Y))/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

Gu T (2007) CST Curation Set: 3409; Year: 2007; Biosample/Treatment: cell line, Baf3(PLXSN-NEO-FLT3 (D835Y))/IL3 withdrawal; Disease: chronic myelogenous leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

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