Ser219
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Home > Phosphorylation Site Page: > Ser219  -  TRF1 (human)

Site Information
SKLLMIIsQKDTFHS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448475

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phosphoamino acid analysis ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Upstream Regulation
Putative in vivo kinases:
ATM (human) ( 1 )
Kinases, in vitro:
ATM (human) ( 1 )
Treatments:
ionizing_radiation ( 1 ) , neocarzinostatin ( 1 ) , wortmannin ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Kishi S, et al. (2001) Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks. J Biol Chem 276, 29282-91
11375976   Curated Info

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