Ser535
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.0.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser535  -  Kv4.3 (rat)

Site Information
YPSTRSPsLSSHSGL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3681504

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
p90RSK (human) ( 1 )
Kinases, in vitro:
p90RSK (human) ( 1 )
Treatments:
fluoromethylketone ( 1 ) , H2O2 ( 1 )

Downstream Regulation
Effects of modification on Kv4.3:
activity, inhibited ( 1 )

References 

1

Lu Z, et al. (2008) Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity. Circ Res 103, 269-78
18599872   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2019 Cell Signaling Technology, Inc.