Ser834
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Home > Phosphorylation Site Page: > Ser834  -  CIITA (human)

Site Information
QELPGRLsFLGtRLT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448443

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , phosphoamino acid analysis ( 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 ) , P388D1 (macrophage) ( 2 )

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 2 )

Downstream Regulation
Effects of modification on biological processes:
transcription, altered ( 2 )

References 

1

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info

2

Li G, Harton JA, Zhu X, Ting JP (2001) Downregulation of CIITA function by protein kinase a (PKA)-mediated phosphorylation: mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines. Mol Cell Biol 21, 4626-35
11416140   Curated Info