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Site Information |
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QRQPSVKyATLVSND SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 448435 |
In vivo Characterization | |
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Downstream Regulation | |
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References | |
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Wołodko K, et al. (2020) Leptin Resistance in the Ovary of Obese Mice is Associated with Profound Changes in the Transcriptome of Cumulus Cells. Cell Physiol Biochem 54, 417-437
32348667 Curated Info |
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You J, et al. (2010) Signaling through Tyr985 of leptin receptor as an age/diet-dependent switch in the regulation of energy balance. Mol Cell Biol 30, 1650-9
20086094 Curated Info |
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Knobelspies H, et al. (2010) Mechanism of attenuation of leptin signaling under chronic ligand stimulation. BMC Biochem 11, 2
20059770 Curated Info |
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Björnholm M, et al. (2007) Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function. J Clin Invest 117, 1354-60
17415414 Curated Info |
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Hekerman P, et al. (2005) Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines. FEBS J 272, 109-19
15634336 Curated Info |
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Bjørbaek C, et al. (2001) Divergent roles of SHP-2 in ERK activation by leptin receptors. J Biol Chem 276, 4747-55
11085989 Curated Info |
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Bjorbak C, et al. (2000) SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985. J Biol Chem 275, 40649-57
11018044 Curated Info |
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Eyckerman S, et al. (2000) Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor. FEBS Lett 486, 33-7
11108838 Curated Info |
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Banks AS, Davis SM, Bates SH, Myers MG (2000) Activation of downstream signals by the long form of the leptin receptor. J Biol Chem 275, 14563-72
10799542 Curated Info |
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Li C, Friedman JM (1999) Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction. Proc Natl Acad Sci U S A 96, 9677-82
10449753 Curated Info |