Ser585
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Home > Phosphorylation Site Page: > Ser585  -  TCF8 (human)

Site Information
GDGNLsPsQPPLKNL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 36552500

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Disease tissue studied:
breast cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ATM (human) ( 1 )
Kinases, in vitro:
ATM (human) ( 1 )
Treatments:
ionizing_radiation ( 1 ) , KU-55933 ( 1 )

Downstream Regulation
Effects of modification on TCF8:
protein stabilization ( 1 )
Effects of modification on biological processes:
DNA repair, induced ( 1 )

References 

1

Zhang P, et al. (2014) ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol 16, 864-75
25086746   Curated Info