Tyr302
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Home > Phosphorylation Site Page: > Tyr302  -  KIR2DL1 (human)

Site Information
QDPQEVTyTQLNHCV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 462345
Associated spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 )
Disease tissue studied:
lung cancer ( 2 , 3 ) , non-small cell lung cancer ( 2 , 3 )
Relevant cell line - cell type - tissue:
293T (epithelial) ( 1 ) , NCI-H1734 (pulmonary) ( 2 , 3 )

Upstream Regulation
Treatments:
vanadate ( 1 )

Downstream Regulation
Effects of modification on KIR2DL1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 )
Induce interaction with:
supervillin (human) ( 1 )

References 

1

Liu HP, et al. (2011) Association of supervillin with KIR2DL1 regulates the inhibitory signaling of natural killer cells. Cell Signal 23, 487-96
21070852   Curated Info

2

Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7
18180459   Curated Info

3

Guo A (2005) CST Curation Set: 933; Year: 2005; Biosample/Treatment: cell line, NCI-H1734/serum starved; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info