Ser472
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Home > Phosphorylation Site Page: > Ser472  -  RELB (human)

Site Information
DFFSGTVsLPGLEPP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 36392502

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
IKKA (human) ( 1 ) , IKKB (human) ( 1 )
Kinases, in vitro:
IKKA (human) ( 1 ) , IKKB (human) ( 1 )
Treatments:
TNF ( 1 )

Downstream Regulation
Effects of modification on RELB:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell motility, induced ( 1 ) , transcription, induced ( 1 )
Inhibit interaction with:
IkB-alpha (human) ( 1 )

References 

1

Authier H, et al. (2014) IKK phosphorylates RelB to modulate its promoter specificity and promote fibroblast migration downstream of TNF receptors. Proc Natl Acad Sci U S A 111, 14794-9
25267645   Curated Info