Ser78
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Home > Phosphorylation Site Page: > Ser78  -  BMAL1 (human)

Site Information
KNAREAHsQIEKRRR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3638466
Associated spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
E.coli (bacterial) ( 1 ) , fibroblast ( 1 ) , HEK293T (epithelial) ( 1 ) , M059K (glial) ( 2 )

Downstream Regulation
Effects of modification on BMAL1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
DNA ( 1 )

References 

1

Wang Z, Wu Y, Li L, Su XD (2013) Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA. Cell Res 23, 213-24
23229515   Curated Info

2

Stokes M (2006) CST Curation Set: 1955; Year: 2006; Biosample1/Treatment/Isotope: cell line, M059K/normal/L, Biosample2/Treatment/Isotope: cell line, M059K/UV/H; Disease: glioblastoma; SILAC: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info